PRDM9 is a trans-acting factor directing meiotic recombination to specific DNA-binding sites
by its zinc finger (ZnF) array. It was suggested that PRDM9 is a multimer; however, we do …

PRDM9 has been identified as a meiosis-specific protein that plays a key role in determining
the location of meiotic recombination hotspots. Although it is well-established that PRDM9 …

Human isocitrate dehydrogenase 1 (IDH1) is a highly conserved enzyme that converts isocitrate
to α-ketoglutarate (αKG). IDH1 mutations affecting residue R132 drive tumor formation, …

Mutations in human isocitrate dehydrogenase 1 (IDH1) drive tumor formation in a variety of
cancers by replacing its conventional activity with a neomorphic activity that generates an …

The Epstein-Barr virus (EBV) is implicated in the induction of several malignancies. The
nuclear antigen 1 (EBNA1) is the only viral protein that is expressed consistently in all EBV-…

Context: Prokineticin 1 (PROK1), also called endocrine gland–derived vascular endothelial
growth factor, is a well-established regulator of endometrial receptivity and placental …

We have previously shown by far-Western blotting that the Epstein—Barr virus nuclear antigen
2 (EBNA-2) both binds to a cellular protein of 130 kDa and histone H1, with the complex …

The members of the H1 histone family can be classified into three groups, which are the main
class subtypes expressed in somatic cells, the developmental- and tissue-specific subtypes…

Filamentous actin structures possess unique biophysical and biochemical properties and
are required for cell locomotion, cell division, compartmentalization and morphological …

Background: The profilins are a group of ubiquitous actin monomer binding proteins that are
responsible for regulating the normal distribution of filamentous actin networks in eukaryotic …