Reciprocal regulation of STING and TCR signaling by mTORC1 for T-cell activation and function
…, M Unno, W Kobayashi, N Yoneda… - Life science …, 2019 - life-science-alliance.org
Stimulator of interferon genes (STING) plays a key role in detecting cytosolic DNA and induces
type I interferon (IFN-I) responses for host defense against pathogens. Although T cells …
type I interferon (IFN-I) responses for host defense against pathogens. Although T cells …
RIPK1 blocks T cell senescence mediated by RIPK3 and caspase-8
T Imanishi, M Unno, N Yoneda, Y Motomura… - Science …, 2023 - science.org
Receptor-interacting protein kinase 1 (RIPK1) regulates cell death and inflammation. Here,
we show that T cell–specific RIPK1 deficiency in mice leads to the premature senescence of …
we show that T cell–specific RIPK1 deficiency in mice leads to the premature senescence of …
[PDF][PDF] mTORC1 signaling controls TLR2-mediated T-cell activation by inducing TIRAP expression
T Imanishi, M Unno, W Kobayashi, N Yoneda, S Akira… - Cell Reports, 2020 - cell.com
Effector, but not naïve, T cells are activated by toll-like receptor-2 (TLR2) stimulation,
leading to cytokine production and proliferation. We found that the differential response is …
leading to cytokine production and proliferation. We found that the differential response is …
[HTML][HTML] Correlations between behavior and hormone concentrations or gut microbiome imply that domestic cats (Felis silvestris catus) living in a group are not like ' …
H Koyasu, H Takahashi, M Yoneda, S Naba… - PLoS …, 2022 - journals.plos.org
Domestic cats (Felis silvestris catus) can live in high densities, although most feline species
are solitary and exclusively territorial animals; it is possible that certain behavioral strategies …
are solitary and exclusively territorial animals; it is possible that certain behavioral strategies …
[HTML][HTML] Styrene maleic acid copolymer-based micellar formation of temoporfin (SMA@ mTHPC) behaves as a nanoprobe for tumor-targeted photodynamic therapy …
…, S Gao, R Islam, H Nema, R Yanagibashi, N Yoneda… - Biomedicines, 2021 - mdpi.com
Tumor-targeted photodynamic therapy (PDT) using polymeric photosensitizers is a promising
anticancer therapeutic strategy. Previously, we developed several polymeric nanoprobes …
anticancer therapeutic strategy. Previously, we developed several polymeric nanoprobes …
Conversion of vitamin D3 to 1α, 25-dihydroxyvitamin D3 by Streptomyces griseolus cytochrome P450SU-1
N Sawada, T Sakaki, S Yoneda, T Kusudo… - Biochemical and …, 2004 - Elsevier
Streptomyces griseolus cytochrome P450SU-1 (CYP105A1) was expressed in Escherichia
coli at a level of 1.0μmol/L culture and purified with a specific content of 18.0nmol/mg protein. …
coli at a level of 1.0μmol/L culture and purified with a specific content of 18.0nmol/mg protein. …
Effects of various types of anesthesia on hemodynamics, cardiac function, and glucose and lipid metabolism in rats
Y Sano, S Ito, M Yoneda, K Nagasawa… - American Journal …, 2016 - journals.physiology.org
Anesthesia can affect respiratory, circulatory, and endocrine systems but is necessary for
certain experimental procedures such as echocardiography and blood sampling in small …
certain experimental procedures such as echocardiography and blood sampling in small …
Mature teratoma arising from an intraabdominal testis in a 2-month-old boy: case report and review of intraabdominal testicular tumors in children
N Tanaka, A Yoneda, M Fukuzawa - Journal of Pediatric Surgery, 2009 - Elsevier
Tumors arising in an undescended testis are rare in infants. We report a mature teratoma in
an intraabdominal testis of a 2-month-old boy. He presented with a large left-sided …
an intraabdominal testis of a 2-month-old boy. He presented with a large left-sided …
[PDF][PDF] Clinical implementation of metabolomics
…, N Nishikata, H Yoshida, J Yoneda… - …, 2012 - openresearchlibrary.org
Metabolomics, which is also referred to as metabonomics, metabolic profiling or metabolic
fingerprinting, is the comprehensive quantitative measurement of endogenous metabolites …
fingerprinting, is the comprehensive quantitative measurement of endogenous metabolites …
Atorvastatin reduces cardiac and adipose tissue inflammation in rats with metabolic syndrome
Y Yamada, S Takeuchi, M Yoneda, S Ito, Y Sano… - International Journal of …, 2017 - Elsevier
Background Statins are strong inhibitors of cholesterol biosynthesis and help to prevent
cardiovascular disease. They also exert additional pleiotropic effects that include an anti-…
cardiovascular disease. They also exert additional pleiotropic effects that include an anti-…