Robust T-cell responses in anti-CD20-treated patients following COVID-19 vaccination: a prospective cohort study

N Madelon, K Lauper, G Breville… - Clinical Infectious …, 2022 - academic.oup.com
Background Patients treated with anti-CD20 therapy are particularly at risk of developing
severe coronavirus disease 2019 (COVID-19); however, little is known regarding COVID-19 …

Omicron-specific cytotoxic T-cell responses after a third dose of mRNA COVID-19 vaccine among patients with multiple sclerosis treated with ocrelizumab

N Madelon, N Heikkilä, IS Royo, P Fontannaz… - JAMA …, 2022 - jamanetwork.com
Importance The SARS-CoV-2 variant B.1.1.529 (Omicron) escapes neutralizing antibodies
elicited after COVID-19 vaccination, while T-cell responses might be better conserved. It is …

Absence of MHC-II expression by lymph node stromal cells results in autoimmunity

…, A Schlaeppi, D Brighouse, N Madelon… - Life science …, 2018 - life-science-alliance.org
How lymph node stromal cells (LNSCs) shape peripheral T-cell responses remains unclear.
We have previously demonstrated that murine LNSCs, lymphatic endothelial cells (LECs), …

[HTML][HTML] A new plasmacytoid dendritic cell-based vaccine in combination with anti-PD-1 expands the tumor-specific CD8+ T cells of lung cancer patients

…, D Laurin, B Caulier, C Aspord, N Madelon… - International Journal of …, 2023 - mdpi.com
The purpose of immune checkpoint inhibitor (ICI)-based therapies is to help the patient’s
immune system to combat tumors by restoring the immune response mediated by CD8+ …

Omicron-specific cytotoxic T-cell responses are boosted following a third dose of mRNA COVID-19 vaccine in anti-CD20-treated multiple sclerosis patients

N Madelon, N Heikkilä, I Sabater Royo, P Fontannaz… - MedRxiv, 2021 - medrxiv.org
Importance The SARS-CoV-2 variant Omicron escapes neutralizing antibody responses
elicited after COVID-19 vaccination, while T-cell responses might be better conserved. It is …

Patients treated with anti-CD20 therapy can mount robust T cell responses to mRNA-based COVID-19 vaccines

N Madelon, K Lauper, G Breville, IS Royo, R Goldstein… - MedRxiv, 2021 - medrxiv.org
Patients treated with anti-CD20 therapy are particularly at risk of developing severe COVID-19,
however little is known regarding COVID-19 vaccine effectiveness in this population. This …

[PDF][PDF] Macroautophagy in dendritic cells controls the homeostasis and stability of regulatory T cells

J Niven, N Madelon, N Page, A Caruso, G Harlé… - Cell reports, 2019 - cell.com
Regulatory T cells (Tregs) play a crucial role in controlling autoimmune and inflammatory
responses. Recent studies have demonstrated that dendritic cells (DCs) contribute to the …

Release of pig leukocytes and reduced human NK cell recruitment during ex vivo perfusion of HLA‐E/human CD 46 double‐transgenic pig limbs with human blood

…, AK Bongoni, A Pradier, N Madelon… - …, 2018 - Wiley Online Library
Background In pig‐to‐human xenotransplantation, interactions between human natural
killer ( NK ) cells and porcine endothelial cells ( pEC ) are characterized by recruitment and …

Human anti‐pig NK cell and CD8+ T‐cell responses in the presence of regulatory dendritic cells

N Madelon, GL Puga Yung, JD Seebach - Xenotransplantation, 2016 - Wiley Online Library
Background Dendritic cells ( DC ) play a major role in natural killer ( NK ) cell and cytotoxic
T lymphocyte ( CTL ) activation leading to cell‐mediated xenogeneic responses. In contrast, …

Prolongation of rat‐to‐mouse islets xenograft survival by co‐transplantation of autologous IL‐10 differentiated murine tolerogenic dendritic cells

N Madelon, E Montanari, L Gruaz, J Pimenta… - …, 2020 - Wiley Online Library
Background Tolerogenic dendritic cells (DCs) represent a promising approach to promote
transplantation tolerance. In this study, the potential of autologous bone marrow (BM)–derived …