Molecular mimicry by Helicobacter pylori CagA protein may be involved in the pathogenesis of H. pylori‐associated chronic idiopathic thrombocytopenic purpura

…, R Nawata, Y Oka, M Shirai… - British journal of …, 2004 - Wiley Online Library
The eradication of Helicobacter pylori often leads to platelet recovery in patients with chronic
idiopathic thrombocytopenic purpura (cITP). Although this clinical observation suggests the …

Helminth infection results in decreased virus-specific CD8+ cytotoxic T-cell and Th1 cytokine responses as well as delayed virus clearance.

JK Actor, M Shirai, MC Kullberg… - Proceedings of the …, 1993 - National Acad Sciences
During the time of egg deposition, schistosome-infected mice exhibit a downregulation in
interleukin 2 and interferon gamma production toward parasite antigens, mitogens, and foreign …

Differences in Genotypes of Helicobacter pylori from Different Human Populations

…, A Chowdhury, S Datta, M Shirai… - Journal of …, 2000 - Am Soc Microbiol
DNA motifs at several informative loci in more than 500 strains ofHelicobacter pylori from five
continents were studied by PCR and sequencing to gain insights into the evolution of this …

Acute hyperglycemia is associated with adverse outcome after acute myocardial infarction in the coronary intervention era

…, K Tsuchihashi, M Yamagishi, Y Ikeda, M Shirai… - American heart …, 2005 - Elsevier
PURPOSE: This study was undertaken to assess the association between acute hyperglycemia
and inhospital outcome after acute myocardial infarction (AMI) in the percutaneous …

Whole-genome analyses reveal genetic instability of Acetobacter pasteurianus

…, S Kuhara, K Matsushita, N Fujita, M Shirai - Nucleic Acids …, 2009 - academic.oup.com
Acetobacter species have been used for brewing traditional vinegar and are known to have
genetic instability. To clarify the mutability, Acetobacter pasteurianus NBRC 3283, which …

Identification of the urease operon in Helicobacter pylori and its control by mRNA decay in response to pH

JK Akada, M Shirai, H Takeuchi, M Tsuda… - Molecular …, 2000 - Wiley Online Library
We investigated the transcription of the urease gene cluster ureABIEFGH in Helicobacter
pylori to determine the regulation of gene expression of the highly produced enzyme urease. …

Comparison of whole genome sequences of Chlamydia pneumoniae J138 from Japan and CWL029 from USA

M Shirai, H Hirakawa, M Kimoto, M Tabuchi… - Nucleic Acids …, 2000 - academic.oup.com
Chlamydia pneumoniae is a widespread pathogen of humans causing pneumonia and
bronchitis. There are many reports of an association between C.pneumoniae infection and …

Helper-cytotoxic T lymphocyte (CTL) determinant linkage required for priming of anti-HIV CD8+ CTL in vivo with peptide vaccine constructs.

M Shirai, CD Pendleton, J Ahlers… - … (Baltimore, Md.: 1950 …, 1994 - journals.aai.org
CTL are a critical component of protective immunity against viral infections, but requirements
for in vivo priming of CTL are not completely understood. Covalent linkage of a helper …

A change in PBP1 is involved in amoxicillin resistance of clinical isolates of Helicobacter pylori

…, MW Chang, H Yanai, K Okita, M Shirai - Journal of …, 2002 - academic.oup.com
Reports on the isolation of amoxicillin-resistant Helicobacter pylori are increasing worldwide,
which may cause serious problems in eradication therapy. To elucidate the mechanism of …

Distribution of Chlamydia pneumoniae Infection in the Atherosclerotic Carotid Artery

K Yamashita, K Ouchi, M Shirai, T Gondo, T Nakazawa… - Stroke, 1998 - Am Heart Assoc
Background and Purpose—Chlamydia pneumoniae infection has recently become noteworthy
in relation to atherosclerosis. We investigated by immunohistochemistry the distribution of …