Human G-MDSCs are neutrophils at distinct maturation stages promoting tumor growth in breast cancer

M Mehmeti-Ajradini, C Bergenfelz… - Life Science …, 2020 - life-science-alliance.org
Myeloid-derived suppressor cells (MDSCs) are known to contribute to immune evasion in
cancer. However, the function of the human granulocytic (G)-MDSC subset during tumor …

AIRE is expressed in breast cancer TANs and TAMs to regulate the extrinsic apoptotic pathway and inflammation

E Källberg, M Mehmeti-Ajradini… - Journal of Leukocyte …, 2024 - academic.oup.com
The autoimmune regulator (AIRE) is a transcriptional regulator expressed in the thymus and
is necessary for maintaining immunological self-tolerance. Extrathymic AIRE expression is …

Function of Innate Immune Cells in Breast Cancer

FB Gunnarsdóttir - 2021 - portal.research.lu.se
Tumor associated macrophages (TAMs) are key cells in creating an immunosuppressive
tumor microenvironment (TME). In general, presence of TAMs is associated with worse …