User profiles for Matthew Zirui Tay

Matthew Zirui Tay

Agency for Science, Technology and Research (A*STAR)
Verified email at idlabs.a-star.edu.sg
Cited by 6150

[HTML][HTML] The trinity of COVID-19: immunity, inflammation and intervention

MZ Tay, CM Poh, L Rénia, PA MacAry… - Nature Reviews …, 2020 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of
the ongoing coronavirus disease 2019 (COVID-19) pandemic. Alongside investigations into …

[HTML][HTML] Antibody-dependent cellular phagocytosis in antiviral immune responses

MZ Tay, K Wiehe, J Pollara - Frontiers in immunology, 2019 - frontiersin.org
Antiviral activities of antibodies may either be dependent only on interactions between the
antibody and cognate antigen, as in binding and neutralization of an infectious virion, or …

[HTML][HTML] Lower vaccine-acquired immunity in the elderly population following two-dose BNT162b2 vaccination is alleviated by a third vaccine dose

…, SW Fong, ZW Chang, NZ Zhuo, MZ Tay… - Nature …, 2022 - nature.com
Understanding the impact of age on vaccinations is essential for the design and delivery of
vaccines against SARS-CoV-2. Here, we present findings from a comprehensive analysis of …

[HTML][HTML] Antibody-mediated internalization of infectious HIV-1 virions differs among antibody isotypes and subclasses

MZ Tay, P Liu, LTD Williams, MD McRaven… - PLoS …, 2016 - journals.plos.org
Emerging data support a role for antibody Fc-mediated antiviral activity in vaccine efficacy
and in the control of HIV-1 replication by broadly neutralizing antibodies. Antibody-mediated …

[HTML][HTML] The role of single-cell technology in the study and control of infectious diseases

WN Lin, MZ Tay, R Lu, Y Liu, CH Chen, LF Cheow - Cells, 2020 - mdpi.com
The advent of single-cell research in the recent decade has allowed biological studies at an
unprecedented resolution and scale. In particular, single-cell analysis techniques such as …

[HTML][HTML] Linear B-cell epitopes in the spike and nucleocapsid proteins as markers of SARS-CoV-2 exposure and disease severity

…, G Carissimo, CM Poh, ZW Chang, MZ Tay… - …, 2020 - thelancet.com
Background Given the unceasing worldwide surge in COVID-19 cases, there is an imperative
need to develop highly specific and sensitive serology assays to define exposure to …

Rare detection of antiviral functions of polyclonal IgA isolated from plasma and breast milk compartments in women chronically infected with HIV-1

MZ Tay, EL Kunz, A Deal, L Zhang, KE Seaton… - Journal of …, 2019 - Am Soc Microbiol
The humoral response to invading mucosal pathogens comprises multiple antibody isotypes
derived from systemic and mucosal compartments. To understand the contribution of each …

Asymptomatic COVID‐19: disease tolerance with efficient anti‐viral immunity against SARS‐CoV‐2

…, A Torres‐Ruesta, CYP Lee, MZ Tay… - EMBO molecular …, 2021 - embopress.org
The immune responses and mechanisms limiting symptom progression in asymptomatic
cases of SARS‐CoV‐2 infection remain unclear. We comprehensively characterized …

Decreased memory B cell frequencies in COVID‐19 delta variant vaccine breakthrough infection

MZ Tay, A Rouers, SW Fong, YS Goh… - EMBO molecular …, 2022 - embopress.org
The SARS‐CoV‐2 Delta (B.1.617.2) variant is capable of infecting vaccinated persons. An
open question remains as to whether deficiencies in specific vaccine‐elicited immune …

[HTML][HTML] Plasmodium vivax binds host CD98hc (SLC3A2) to enter immature red blood cells

B Malleret, A El Sahili, MZ Tay, G Carissimo… - Nature …, 2021 - nature.com
More than one-third of the world’s population is exposed to Plasmodium vivax malaria, mainly
in Asia 1 . P. vivax preferentially invades reticulocytes (immature red blood cells) 2 , 3 – 4 . …