User profiles for Matthew Zirui Tay
Matthew Zirui TayAgency for Science, Technology and Research (A*STAR) Verified email at idlabs.a-star.edu.sg Cited by 6150 |
[HTML][HTML] The trinity of COVID-19: immunity, inflammation and intervention
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of
the ongoing coronavirus disease 2019 (COVID-19) pandemic. Alongside investigations into …
the ongoing coronavirus disease 2019 (COVID-19) pandemic. Alongside investigations into …
[HTML][HTML] Antibody-dependent cellular phagocytosis in antiviral immune responses
MZ Tay, K Wiehe, J Pollara - Frontiers in immunology, 2019 - frontiersin.org
Antiviral activities of antibodies may either be dependent only on interactions between the
antibody and cognate antigen, as in binding and neutralization of an infectious virion, or …
antibody and cognate antigen, as in binding and neutralization of an infectious virion, or …
[HTML][HTML] Lower vaccine-acquired immunity in the elderly population following two-dose BNT162b2 vaccination is alleviated by a third vaccine dose
Understanding the impact of age on vaccinations is essential for the design and delivery of
vaccines against SARS-CoV-2. Here, we present findings from a comprehensive analysis of …
vaccines against SARS-CoV-2. Here, we present findings from a comprehensive analysis of …
[HTML][HTML] Antibody-mediated internalization of infectious HIV-1 virions differs among antibody isotypes and subclasses
MZ Tay, P Liu, LTD Williams, MD McRaven… - PLoS …, 2016 - journals.plos.org
Emerging data support a role for antibody Fc-mediated antiviral activity in vaccine efficacy
and in the control of HIV-1 replication by broadly neutralizing antibodies. Antibody-mediated …
and in the control of HIV-1 replication by broadly neutralizing antibodies. Antibody-mediated …
[HTML][HTML] The role of single-cell technology in the study and control of infectious diseases
The advent of single-cell research in the recent decade has allowed biological studies at an
unprecedented resolution and scale. In particular, single-cell analysis techniques such as …
unprecedented resolution and scale. In particular, single-cell analysis techniques such as …
[HTML][HTML] Linear B-cell epitopes in the spike and nucleocapsid proteins as markers of SARS-CoV-2 exposure and disease severity
Background Given the unceasing worldwide surge in COVID-19 cases, there is an imperative
need to develop highly specific and sensitive serology assays to define exposure to …
need to develop highly specific and sensitive serology assays to define exposure to …
Rare detection of antiviral functions of polyclonal IgA isolated from plasma and breast milk compartments in women chronically infected with HIV-1
MZ Tay, EL Kunz, A Deal, L Zhang, KE Seaton… - Journal of …, 2019 - Am Soc Microbiol
The humoral response to invading mucosal pathogens comprises multiple antibody isotypes
derived from systemic and mucosal compartments. To understand the contribution of each …
derived from systemic and mucosal compartments. To understand the contribution of each …
Asymptomatic COVID‐19: disease tolerance with efficient anti‐viral immunity against SARS‐CoV‐2
The immune responses and mechanisms limiting symptom progression in asymptomatic
cases of SARS‐CoV‐2 infection remain unclear. We comprehensively characterized …
cases of SARS‐CoV‐2 infection remain unclear. We comprehensively characterized …
Decreased memory B cell frequencies in COVID‐19 delta variant vaccine breakthrough infection
The SARS‐CoV‐2 Delta (B.1.617.2) variant is capable of infecting vaccinated persons. An
open question remains as to whether deficiencies in specific vaccine‐elicited immune …
open question remains as to whether deficiencies in specific vaccine‐elicited immune …
[HTML][HTML] Plasmodium vivax binds host CD98hc (SLC3A2) to enter immature red blood cells
More than one-third of the world’s population is exposed to Plasmodium vivax malaria, mainly
in Asia 1 . P. vivax preferentially invades reticulocytes (immature red blood cells) 2 , 3 – 4 . …
in Asia 1 . P. vivax preferentially invades reticulocytes (immature red blood cells) 2 , 3 – 4 . …