Although the exact etiology of Alzheimer's disease (AD) is a topic of debate, the consensus
is that the accumulation of β-amyloid (Aβ) peptides in the senile plaques is one of the …

Partial resistance of cell membranes to solubilization with mild detergents and the analysis
of isolated detergent-resistant membranes (DRMs) have been used operationally to define …

The flotillins/reggie proteins are associated with noncaveolar membrane microdomains and
have been implicated in the regulation of a clathrin- and caveolin-independent endocytosis …

In mammals, two isoforms of the peroxisome targeting signal (PTS) type 1 receptor Pex5p,
ie Pex5pS and Pex5pL with an internal 37-amino acid insertion, have previously been …

Peroxisome-biogenesis disorders (PBDs), including Zellweger syndrome (ZS), are autosomal
recessive diseases caused by a deficiency in peroxisome assembly as well as by a …

To investigate peroxisome assembly and human peroxisome biogenesis disorders (PBDs)
such as Zellweger syndrome, thirteen different complementation groups (CGs) of Chinese …

RNA interference (RNAi) is a ubiquitous mechanism of eukaryotic gene regulation that can
be exploited for specific gene silencing. Retroviruses have been successfully used for stable …

Plasmalogens are a major subclass of ethanolamine and choline glycerophospholipids in
which a long chain fatty alcohol is attached at the sn-1 position through a vinyl ether bond. …

Plasmalogens, mostly ethanolamine‐containing alkenyl ether phospholipids, are a major
subclass of glycerophospholipids. Plasmalogen synthesis is initiated in peroxisomes and …

Peroxisome number and quality are maintained by its biogenesis and turnover and are
important for the homeostasis of peroxisomes. Peroxisomes are increased in number by division …