Background The gut microbiota plays a central role in host physiology and in several pathological
mechanisms in humans. Antibiotics compromise the composition and functions of the …

Different gastrointestinal disorders, including inflammatory bowel diseases (IBD), have been
linked to alterations of the gut microbiota composition, namely dysbiosis. Fecal microbiota …

Colorectal cancer (CRC) is a multifaceted disease influenced by both environmental and
genetic factors. A large body of literature has demonstrated the role of gut microbes in …

TGF-β pathway is generally associated with the processes of metastasis, angiogenesis and
EMT in cancer. Very little is known, however, about the role of TGF-β in cancer drug …

iNKT cells account for a relevant fraction of effector T-cells in the intestine and are considered
an attractive platform for cancer immunotherapy. Although iNKT cells are cytotoxic …

Cigarette smoking impairs the lung innate immune response making smokers more susceptible
to infections and severe symptoms. Dysregulation of cell death is emerging as a key …

Inflammatory bowel disease (IBD) pathogenesis has been linked to the aberrant activation
of the Gut-associated lymphoid tissues against components of the intestinal microbiota. …

Quantification of oxidative stress is a challenging task that can help in monitoring chronic
inflammatory respiratory airway diseases. Different studies can be found in the literature …

Background and Aims T helper 17 [Th17] cells are crucially involved in the immunopathogenesis
of inflammatory bowel diseases in humans. Nevertheless, pharmacological blockade of …

Background Atherosclerosis is a slowly progressing, chronic multifactorial disease characterized
by the accumulation of lipids, inflammatory cells, and fibrous tissue that drives to the …