Mechanical stimuli drive many physiological processes, including touch and pain sensation,
hearing, and blood pressure regulation. Mechanically activated (MA) cation channel …

Mechanotransduction has an important role in physiology. Biological processes including
sensing touch and sound waves require as-yet-unidentified cation channels that detect …

Purpose: Doctoral student well-being is an important matter that shapes the well-being of
academics throughout their careers. Given that well-being has been found to be closely related …

Neurotransmitters are released at presynaptic active zones (AZs). In the fly Drosophila,
monoclonal antibody (MAB) nc82 specifically labels AZs. We employ nc82 to identify Bruchpilot …

The molecular organization of presynaptic active zones during calcium influx–triggered
neurotransmitter release is the focus of intense investigation. The Drosophila coiled-coil domain …

Comprehensive, reproducible and precise analysis of large sample cohorts is one of the
key objectives of quantitative proteomics. Here, we present an implementation of data-…

The insulin‐resistant brain state is related to late‐onset sporadic Alzheimer's disease, and
alterations in the insulin receptor (IR) and its downstream phosphatidylinositol‐3 kinase …

A comparative study of quantitative kinematic data of fore- and hindlimb movements of eight
different mammalian species leads to the recognition of basic principles in the locomotion of …

Transient receptor potential A1 (TRPA1) ion channel senses a variety of noxious stimuli and
is involved in nociception. Many TRPA1 agonists covalently modify the channel, which can …

Piezo1 and Piezo2 encode mechanically activated cation channels that function as
mechanotransducers involved in vascular system development and touch sensing, respectively. …