User profiles for Manolis Maragkakis
Emmanouil (Manolis) MaragkakisStadtman Principal Investigator, NIA/NIH Verified email at nih.gov Cited by 5926 |
Lost in translation: an assessment and perspective for computational microRNA target identification
P Alexiou, M Maragkakis, GL Papadopoulos… - …, 2009 - academic.oup.com
MicroRNAs (miRNAs) are a class of short endogenously expressed RNA molecules that
regulate gene expression by binding directly to the messenger RNA of protein coding genes. …
regulate gene expression by binding directly to the messenger RNA of protein coding genes. …
DIANA-microT web server: elucidating microRNA functions through target prediction
M Maragkakis, M Reczko, VA Simossis… - Nucleic acids …, 2009 - academic.oup.com
Computational microRNA (miRNA) target prediction is one of the key means for deciphering
the role of miRNAs in development and disease. Here, we present the DIANA-microT web …
the role of miRNAs in development and disease. Here, we present the DIANA-microT web …
TarBase 6.0: capturing the exponential growth of miRNA targets with experimental support
As the relevant literature and the number of experiments increase at a super linear rate,
databases that curate and collect experimentally verified microRNA (miRNA) targets have …
databases that curate and collect experimentally verified microRNA (miRNA) targets have …
DIANA miRPath v. 2.0: investigating the combinatorial effect of microRNAs in pathways
MicroRNAs (miRNAs) are key regulators of diverse biological processes and their functional
analysis has been deemed central in many research pipelines. The new version of DIANA-…
analysis has been deemed central in many research pipelines. The new version of DIANA-…
Functional microRNA targets in protein coding sequences
Motivation: Experimental evidence has accumulated showing that microRNA (miRNA)
binding sites within protein coding sequences (CDSs) are functional in controlling gene …
binding sites within protein coding sequences (CDSs) are functional in controlling gene …
[HTML][HTML] Accurate microRNA target prediction correlates with protein repression levels
M Maragkakis, P Alexiou, GL Papadopoulos… - BMC …, 2009 - Springer
Background MicroRNAs are small endogenously expressed non-coding RNA molecules
that regulate target gene expression through translation repression or messenger RNA …
that regulate target gene expression through translation repression or messenger RNA …
DIANA-LncBase: experimentally verified and computationally predicted microRNA targets on long non-coding RNAs
Recently, the attention of the research community has been focused on long non-coding
RNAs (lncRNAs) and their physiological/pathological implications. As the number of …
RNAs (lncRNAs) and their physiological/pathological implications. As the number of …
DIANA-mirPath: Integrating human and mouse microRNAs in pathways
GL Papadopoulos, P Alexiou, M Maragkakis… - …, 2009 - academic.oup.com
DIANA-mirPath is a web-based computational tool developed to identify molecular pathways
potentially altered by the expression of single or multiple microRNAs. The software …
potentially altered by the expression of single or multiple microRNAs. The software …
[HTML][HTML] Editing of Epstein-Barr virus-encoded BART6 microRNAs controls their dicer targeting and consequently affects viral latency
Certain primary transcripts of miRNA (pri-microRNAs) undergo RNA editing that converts
adenosine to inosine. The Epstein-Barr virus (EBV) genome encodes multiple microRNA …
adenosine to inosine. The Epstein-Barr virus (EBV) genome encodes multiple microRNA …
Mili and Miwi target RNA repertoire reveals piRNA biogenesis and function of Miwi in spermiogenesis
Germ cells implement elaborate mechanisms to protect their genetic material and to
regulate gene expression during differentiation. Piwi proteins bind Piwi-interacting RNAs (piRNAs), …
regulate gene expression during differentiation. Piwi proteins bind Piwi-interacting RNAs (piRNAs), …