Over the past decade, the Nomenclature Committee on Cell Death (NCCD) has formulated
guidelines for the definition and interpretation of cell death from morphological, biochemical, …

Ferroptosis is a form of regulated cell death characterized by the iron-dependent accumulation
of lipid hydroperoxides to lethal levels. Emerging evidence suggests that ferroptosis …

For decades, authors have described unusual cell structures, referred to as cell-in-cell
structures, in which whole cells are found in the cytoplasm of other cells. One well-characterized …

In a screen for gene copy-number changes in mouse mammary tumors, we identified a tumor
with a small 350-kb amplicon from a region that is syntenic to a much larger locus amplified …

The design of cancer-targeting particles with precisely tuned physicochemical properties
may enhance the delivery of therapeutics and access to pharmacological targets. However, a …

Epithelial cells require attachment to extracellular matrix (ECM) to suppress an apoptotic
cell death program termed anoikis. Here we describe a nonapoptotic cell death program in …

… & Conrad, M. Role of GPX4 in ferroptosis and its … & Gunzburger, M. Grid generation and
optimization based on centroidal … We thank members of the Overholtzer laboratory for helpful …

Autophagy normally involves the formation of double-membrane autophagosomes that
mediate bulk cytoplasmic and organelle degradation. Here we report the modification of single-…

The Hippo signalling pathway regulates cellular proliferation and survival, thus has profound
effects on normal cell fate and tumorigenesis 1 , 2 , 3 . The pivotal effector of this pathway is …

… MHC-I heavy chain (HC) that has newly translocated into the ER is chaperoned by Calnexin
and the oxidoreductase ERp57 and associates with β2-microglobulin (β2 m) followed by …