Reactive oxygen species (ROS) play critical roles in self-renewal division for various stem
cell types. However, it remains unclear how ROS signals are integrated with self-renewal …

The testis is an immune-privileged organ. It is considered that the testis somatic
microenvironment is responsible for immune suppression. However, immunological properties of …

Extensive application of zinc oxide (ZnO) nanoparticles (NPs) in everyday life results in
increased exposure to these NPs. Spermatogonial stem cells (SSCs) guarantee sperm …

Chronic non-communicable diseases share the pathomechanism of increased reactive
oxygen species (ROS) production by nicotinamide adenine dinucleotide phosphate (NADPH) …

Background— Increased production of reactive oxygen species (ROSs) by angiotensin II (Ang
II) is involved in the initiation and progression of cardiovascular diseases. NADPH …

The aim of this study was to investigate the effects of different oxygen (O 2 ) concentrations
on the growth of mouse spermatogonial stem cells (SSCs) and the possible mechanisms of …

Human male reproductive development has a prolonged prepubertal period characterized
by juvenile quiescence of germ cells with immature spermatogonial stem cell (SSC) …

The estrogen-like effect of bisphenol A (BPA) disrupting the maintenance of functional male
germ cells is associated with male sub-fertility. This study investigated toxicity of male germ …

Infertility is a globally under-recognized public health problem significantly impacting individual
health and socioeconomics affecting millions of couples. The reasons for infertility are …

Female germline stem cells (FGSCs) are adult stem cells that can both self-renew and
differentiate into mature oocytes. Although small-molecule compounds are capable of regulating …