Identification of host determinants of coronavirus infection informs mechanisms of viral
pathogenesis and can provide new drug targets. Here we demonstrate that mammalian SWItch/…

Plitidepsin, a marine-derived cyclic-peptide, inhibits SARS-CoV-2 replication at nanomolar
concentrations by targeting the host protein eukaryotic translation elongation factor 1A. Here, …

Variants of SARS-CoV-2 have become a major public health concern due to increased
transmissibility, and escape from natural immunity, vaccine protection, and monoclonal antibody …

Background Target antigen (Ag) loss has emerged as a major cause of relapse after chimeric
antigen receptor T (CART)-cell therapy. We reasoned that the combination of CART cells, …

A series of SARS-CoV-2 variants of concern (VOCs) have evolved in humans during the
COVID-19 pandemic—Alpha, Beta, Gamma, Delta, and Omicron. Here, we used global …

Although no known asteroid poses a threat to Earth for at least the next century, the catalogue
of near-Earth asteroids is incomplete for objects whose impacts would produce regional …

Peptide based hydrogels have received much attention due to their potential biomedical
applications. The majority of the gel forming peptides present a β-sheet motif that is composed …

Aim To asses if telemedicine with telemonitoring is a clinically useful and safe tool for
monitoring patients with COVID-19. Methods A prospective observational study of patients with …

Information processing in the visual cortex depends on complex and context sensitive patterns
of interactions between neuronal groups in many different cortical areas. Methods used to …

A fundamental question in microbiology is whether there is continuum of genetic diversity
among genomes, or clear species boundaries prevail instead. Whole-genome similarity …