Over the past decade, the data-independent acquisition mode has gained popularity for
broad coverage of complex proteomes by LC-MS/MS and quantification of low-abundance …

In this article, we provide a proteomic reference dataset that has been initially generated for
a benchmarking of software tools for Data-Independent Acquisition (DIA) analysis. This large …

Objective Gain a better understanding of sex-specific differences in individuals with global
developmental delay (GDD), with a focus on phenotypes and genotypes. Methods Using the …

The 3D conformation of the chromatin creates complex networks of noncoding regulatory
regions (distal elements) and promoters impacting gene regulation. Despite the importance of …

Depuis ces vingt dernières années et la démocratisation des technologies de séquençage
haut débit de l'ADN, l'accessibilité des données génomiques a permis le développement de …

Background: The exponential growth of high-throughput sequencing technologies was an
incredible opportunity for researchers to combine different -omics within computational …

The 3D chromatin architecture establishes a complex network of genes and regulatory
elements necessary for transcriptomic regulation in development and disease. This network can …

Background The 3-dimensional (3D) conformation of the chromatin creates complex networks
of noncoding regulatory regions (distal elements) and genes with important implications in …

A large proportion of genetic variations involved in complex diseases are rare and located
within non-coding regions, making the interpretation of underlying biological mechanisms a …