The intracellular signal transduction pathway by which the yeast Saccharomyces cerevisiae
responds to the presence of peptide mating pheromone in its surroundings is one of the best …

BMP is thought to induce hESC differentiation toward multiple lineages including mesoderm
and trophoblast. The BMP-induced trophoblast phenotype is a long-standing paradox in …

The RAD1 and RAD10 genes of Saccharomyces cerevisiae are required for both nucleotide
excision repair and certain mitotic recombination events. Here, model recombination and …

Mitogen-activated protein kinase (MAPK) cascades are conserved signalling modules that
regulate responses to diverse extracellular stimuli, developmental cues and environmental …

Haploid cells of budding yeast Saccharomyces cerevisiae respond to mating pheromones
by inducing genes required for conjugation, arresting cell cycle progression, and undergoing …

Signaling molecules such as Cdc42 and mitogen-activated protein kinases (MAPKs) can
function in multiple pathways in the same cell. Here, we propose one mechanism by which …

Yeast RNA polymerase II initiation factor b, homolog of human TFIIH, is a protein kinase
capable of phosphorylating the C-terminal repeat domain of the polymerase; it possesses a DNA…

Comparison by subtractive hybridization of mRNAs revealed a moderately abundant
message in highly tumorigenic CHEF/16 cells present at very low levels in closely related …

The mitogen-activated protein kinase (MAPK) Kss1 has a dual role in regulating filamentous
(invasive) growth of the yeast Saccharomyces cerevisiae. The stimulatory function of Kss1 …

Signals transmitted by common components often elicit distinct (yet appropriate) outcomes.
In yeast, two developmental options—mating and invasive growth—are both regulated by the …