Exposure to stressful life events increases the risk for psychiatric disorders. Mechanistic insight
into the genetic factors moderating the impact of stress can increase our understanding of …

Oct4, along with Sox2 and Klf4 (SK), can induce pluripotency but structurally similar factors
like Oct6 cannot. To decode why Oct4 has this unique ability, we compare Oct4-binding, …

… EBNA3A protein levels were normalized to GAPDH and are given as x-fold expression
relative to the expression level in the corresponding wt LCL. (D) Flow cytometric analysis of …

Genomic binding of transcription factors, like the glucocorticoid receptor (GR), is linked to
the regulation of genes. However, as we show here, GR binding is a poor predictor of GR-…

… For our study, we re-analyzed publicly available primary data sets and correlated signal
intensities of transcription factors either at a genome wide level or by focusing on EBNA2 …

… According to our protocol (Figure 1A), infection was performed on the hiPSC level; subsequent
puromycin selection was performed to enrich for S-, SO-, or SON-hiPSC and followed by …

… data provide preliminary evidence that the functional SNPs that modulate the transcriptomic
response to stress also associate with differences in the stress response at the system level. …

We present the software Condition-specific Regulatory Units Prediction (CRUP) to infer from
epigenetic marks a list of regulatory units consisting of dynamically changing enhancers …

… degree of variability in the level of activation observed between individual clones with the
same GBS variant (Fig 2C). However, when we averaged the level of activation across clonal …

… For example, we find the highest mean expression level for genes associated with clusters
B and C, that show the most prominent signatures of active enhancers (Figure 3B). In contrast…