Establishment and characterization of a unique human cell line that proliferates dependently on GM‐CSF, IL‐3, or erythropoietin

…, S Chiba, T Kuwaki, K Miyagawa… - Journal of cellular …, 1989 - Wiley Online Library
We have established a novel cell line, designated as TF‐1, from a patient with erythroleukemia,
which showed complete growth dependency on granulocyte‐macrophage colony‐…

[HTML][HTML] DNA double-strand break repair pathway regulates PD-L1 expression in cancer cells

…, KD Held, Y Suzuki, K Kono, K Miyagawa… - Nature …, 2017 - nature.com
Accumulating evidence suggests that exogenous cellular stress induces PD-L1 upregulation
in cancer. A DNA double-strand break (DSB) is the most critical type of genotoxic stress, but …

Subnuclear localization of WT1 in splicing or transcription factor domains is regulated by alternative splicing

SH Larsson, JP Charlieu, K Miyagawa, D Engelkamp… - Cell, 1995 - cell.com
WT1 is a tumor suppressor gene with a key role in urogenital development and the
pathogenesis of Wilms' tumor. Two alternative splice sites in the WT1 transcript allow the gene to …

Targeting DNA damage response in cancer therapy

N Hosoya, K Miyagawa - Cancer science, 2014 - Wiley Online Library
Cancer chemotherapy and radiotherapy are designed to kill cancer cells mostly by inducing
DNA damage. DNA damage is normally recognized and repaired by the intrinsic DNA …

New international formulation for the viscosity of H2O

…, IN Metaxa, E Vogel, R Mareš, K Miyagawa - Journal of Physical …, 2009 - pubs.aip.org
The International Association for the Properties of Water and Steam (IAPWS) encouraged an
extensive research effort to update the IAPS Formulation 1985 for the Viscosity of Ordinary …

DNA damage-dependent acetylation and ubiquitination of H2AX enhances chromatin dynamics

…, S Nishikubo, T Ito, A Muto, K Miyagawa… - … and cellular biology, 2007 - Taylor & Francis
Chromatin reorganization plays an important role in DNA repair, apoptosis, and cell cycle
checkpoints. Among proteins involved in chromatin reorganization, TIP60 histone …

[HTML][HTML] Extremotolerant tardigrade genome and improved radiotolerance of human cultured cells by tardigrade-unique protein

…, H Sagara, T Miura, S Yokobori, K Miyagawa… - Nature …, 2016 - nature.com
Tardigrades, also known as water bears, are small aquatic animals. Some tardigrade
species tolerate almost complete dehydration and exhibit extraordinary tolerance to various …

Mutations of a novel human RAD54 homologue, RAD54B, in primary cancer

…, K Sumii, G Kajiyama, N Kamada, K Miyagawa… - Oncogene, 1999 - nature.com
Association of breast tumor susceptibility gene products BRCA1 and BRCA2 with the RAD51
recombination protein suggested that cancer could arise through defects in recombination. …

[PDF][PDF] Human Rad52 promotes XPG-mediated R-loop processing to initiate transcription-associated homologous recombination repair

…, M Yamauchi, S Nakada, A Shibata, K Miyagawa - Cell, 2018 - cell.com
Given that genomic DNA exerts its function by being transcribed, it is critical for the
maintenance of homeostasis that DNA damage, such as double-strand breaks (DSBs), within …

New international formulation for the thermal conductivity of H2O

…, MJ Assael, IN Metaxa, K Miyagawa… - Journal of Physical …, 2012 - pubs.aip.org
The International Association for the Properties of Water and Steam (IAPWS) encouraged an
extensive research effort to update the IAPS Formulation 1985 for the Thermal Conductivity …