Identification of evolutionarily conserved gene networks mediating neurodegenerative dementia
V Swarup, FI Hinz, JE Rexach, K Noguchi… - Nature medicine, 2019 - nature.com
Identifying the mechanisms through which genetic risk causes dementia is an imperative for
new therapeutic development. Here, we apply a multistage, systems biology approach to …
new therapeutic development. Here, we apply a multistage, systems biology approach to …
[HTML][HTML] Hydrogenase-3 Contributes to Anaerobic Acid Resistance of Escherichia coli
Background Hydrogen production by fermenting bacteria such as Escherichia coli offers a
potential source of hydrogen biofuel. Because H 2 production involves consumption of 2H + , …
potential source of hydrogen biofuel. Because H 2 production involves consumption of 2H + , …
Functional Domains of Pho81p, an Inhibitor of Pho85p Protein Kinase, in the Transduction Pathway of Pi Signals in Saccharomyces cerevisiae
N Ogawa, KI Noguchi, H Sawai… - … and Cellular Biology, 1995 - Taylor & Francis
The PHO81 gene is thought to encode an inhibitor of the negative regulators (Pho80p and
Pho85p) in the phosphatase (PHO) regulon. Transcription of PHO81 is regulated by P i …
Pho85p) in the phosphatase (PHO) regulon. Transcription of PHO81 is regulated by P i …
[HTML][HTML] Cytoplasmic Acidification and the Benzoate Transcriptome in Bacillus subtilis
Background Bacillus subtilis encounters a wide range of environmental pH. The bacteria
maintain cytoplasmic pH within a narrow range. Response to acid stress is a poorly understood …
maintain cytoplasmic pH within a narrow range. Response to acid stress is a poorly understood …
TGFβ-induced expression of long noncoding lincRNA Platr18 controls breast cancer axonogenesis
…, C Fréreux, C Obellianne, K Noguchi… - Life Science …, 2022 - life-science-alliance.org
Metastasis is the leading driver of cancer-related death. Tumor cell plasticity associated with
the epithelial–mesenchymal transition (EMT), an embryonic program also observed in …
the epithelial–mesenchymal transition (EMT), an embryonic program also observed in …
[HTML][HTML] Equivalent hypertrophy and strength gains in β-hydroxy-β-methylbutyrate-or leucine-supplemented men
…, EPT Wong, EA Nunes, KS Noguchi… - Medicine and science …, 2019 - ncbi.nlm.nih.gov
Ingestion of proteins with high leucine content during resistance training (RT) can augment
hypertrophy. Some data suggest that a leucine metabolite, β-hydroxy, β-methylbutyrate (HMB)…
hypertrophy. Some data suggest that a leucine metabolite, β-hydroxy, β-methylbutyrate (HMB)…
[HTML][HTML] Interleukin-like EMT inducer regulates partial phenotype switching in MITF-low melanoma cell lines
K Noguchi, AC Dalton, BV Howley, BJ McCall… - PLoS …, 2017 - journals.plos.org
ILEI (FAM3C) is a secreted factor that contributes to the epithelial-to-mesenchymal transition
(EMT), a cell biological process that confers metastatic properties to a tumor cell. Initially, we …
(EMT), a cell biological process that confers metastatic properties to a tumor cell. Initially, we …
Expression of a tumor-associated antigen RCAS1 in hepatocellular carcinoma
K Noguchi, M Enjoji, M Nakamuta, M Nakashima… - Cancer letters, 2001 - Elsevier
RCAS1 has been reported as a tumor-associated antigen in uterine and ovarian carcinomas.
In vitro studies on RCAS1 indicated that it might function as an apoptosis-inducing factor …
In vitro studies on RCAS1 indicated that it might function as an apoptosis-inducing factor …
[HTML][HTML] Interleukin-like EMT inducer (ILEI) promotes melanoma invasiveness and is transcriptionally up-regulated by upstream stimulatory factor-1 (USF-1)
K Noguchi, TA Dincman, AC Dalton, BV Howley… - Journal of Biological …, 2018 - ASBMB
Interleukin-like EMT inducer (ILEI, FAM3C) is a secreted factor that contributes to the
epithelial-to-mesenchymal transition (EMT), a cell-biological process that confers metastatic …
epithelial-to-mesenchymal transition (EMT), a cell-biological process that confers metastatic …
In vivo serial evaluation of superparamagnetic iron‐oxide labeled stem cells by off‐resonance positive contrast
Y Suzuki, CH Cunningham, K Noguchi… - … in Medicine: An …, 2008 - Wiley Online Library
MRI is emerging as a diagnostic modality to track iron‐oxide‐labeled stem cells. This study
investigates whether an off‐resonance (OR) pulse sequence designed to generate positive …
investigates whether an off‐resonance (OR) pulse sequence designed to generate positive …