Value of in vivo α‐synuclein deposits in Parkinson's disease: A systematic review and meta‐analysis
K Tsukita, H Sakamaki‐Tsukita, K Tanaka… - Movement …, 2019 - Wiley Online Library
Previous studies that have investigated the potential of in vivo abnormal α‐synuclein
deposits as a pathological biomarker for PD included few participants and reported different …
deposits as a pathological biomarker for PD included few participants and reported different …
Phase separation of an actin nucleator by junctional microtubules regulates epithelial function
K Tsukita, M Kitamata, H Kashihara, T Yano… - Science …, 2023 - science.org
Liquid-liquid phase separation (LLPS) is involved in various dynamic biological phenomena.
In epithelial cells, dynamic regulation of junctional actin filaments tethered to the apical …
In epithelial cells, dynamic regulation of junctional actin filaments tethered to the apical …
Long-term effect of regular physical activity and exercise habits in patients with early Parkinson disease
K Tsukita, H Sakamaki-Tsukita, R Takahashi - Neurology, 2022 - AAN Enterprises
Background and Objectives Owing to the lack of long-term observations or comprehensive
adjustment for confounding factors, reliable conclusions regarding long-term effects of …
adjustment for confounding factors, reliable conclusions regarding long-term effects of …
A microtubule‐LUZP1 association around tight junction promotes epithelial cell apical constriction
T Yano, K Tsukita, H Kanoh, S Nakayama… - The EMBO …, 2021 - embopress.org
Apical constriction is critical for epithelial morphogenesis, including neural tube formation.
Vertebrate apical constriction is induced by di‐phosphorylated myosin light chain (ppMLC)‐…
Vertebrate apical constriction is induced by di‐phosphorylated myosin light chain (ppMLC)‐…
High-throughput CSF proteomics and machine learning to identify proteomic signatures for Parkinson disease development and progression
K Tsukita, H Sakamaki-Tsukita, S Kaiser, L Zhang… - Neurology, 2023 - AAN Enterprises
Background and Objectives This study aimed to identify CSF proteomic signatures characteristic
of Parkinson disease (PD) and evaluate their clinical utility. Methods This observational …
of Parkinson disease (PD) and evaluate their clinical utility. Methods This observational …
[HTML][HTML] Reciprocal association between the apical junctional complex and AMPK: a promising therapeutic target for epithelial/endothelial barrier function?
K Tsukita, T Yano, A Tamura, S Tsukita - International Journal of …, 2019 - mdpi.com
Epithelial/endothelial cells adhere to each other via cell–cell junctions including tight junctions
(TJs) and adherens junctions (AJs). TJs and AJs are spatiotemporally and functionally …
(TJs) and adherens junctions (AJs). TJs and AJs are spatiotemporally and functionally …
Dual-color live imaging unveils stepwise organization of multiple basal body arrays by cytoskeletons
…, T Katsuno, H Kashihara, H Tanaka, K Tsukita… - EMBO …, 2024 - embopress.org
For mucociliary clearance of pathogens, tracheal multiciliated epithelial cells (MCCs) organize
coordinated beating of cilia, which originate from basal bodies (BBs) with basal feet (BFs) …
coordinated beating of cilia, which originate from basal bodies (BBs) with basal feet (BFs) …
Vinculin is critical for the robustness of the epithelial cell sheet paracellular barrier for ions
…, H Tanaka, T Mizuno, H Kanoh, K Tsukita… - Life science …, 2019 - life-science-alliance.org
The paracellular barrier function of tight junctions (TJs) in epithelial cell sheets is robustly
maintained against mechanical fluctuations, by molecular mechanisms that are poorly …
maintained against mechanical fluctuations, by molecular mechanisms that are poorly …
Novel pathogenic VPS13A gene mutations in Japanese patients with chorea-acanthocytosis
…, T Fujii, K Tsukita, H Sakamaki-Tsukita… - Neurology …, 2019 - AAN Enterprises
Objective To identify mutations in vacuolar protein sorting 13A (VPS13A) for Japanese patients
with suspected chorea-acanthocytosis (ChAc). Methods We performed a comprehensive …
with suspected chorea-acanthocytosis (ChAc). Methods We performed a comprehensive …
[HTML][HTML] Lower Circulating Lymphocyte Count Predicts ApoE ε4‐Related Cognitive Decline in Parkinson's Disease
K Tsukita, H Sakamaki‐Tsukita… - Movement Disorders, 2021 - ncbi.nlm.nih.gov
4. Dexter DT, Carayon A, Javoy-agid F, et al. Alterations in the levels of iron, ferritin and
other trace metals in parkinson's disease and other neurodegenerative diseases affecting …
other trace metals in parkinson's disease and other neurodegenerative diseases affecting …