The major function of B lymphocytes is to sense antigens and to produce protective antibodies
after activation. This function requires the expression of a B-cell antigen receptor (BCR), …

Optogenetic tools allow isolated, functional investigations of almost any signaling molecule
within complex signaling pathways. A major obstacle is the controlled delivery of light to the …

During the progression of autoimmune (type 1) diabetes, T cells and macrophages infiltrate
the pancreas, disrupt islet function, and destroy insulin-producing beta cells. B-lymphocytes, …

Optogenetic tools have been gaining popularity, in part because they can be used to
decipher the wiring of signaling pathways. They are based on the ability of photoactivatable …

… Kathrin Brenker and Luis Köbele are the driving force behind this project. They are responsible
for the product development and certification process. This consortium is always eager to …

B-lymphocytes have been implicated in many autoimmune diseases, and non-obese
diabetic (NOD) mice that lack B cells do not develop spontaneous autoimmune diabetes. The …