Human papillomavirus G-quadruplexes

K Tluckova, M Marusic, P Tothova, L Bauer… - Biochemistry, 2013 - ACS Publications
Infection with human papillomaviruses (HPVs) is one of the most common sexually transmitted
infections and can lead to development of head and neck, skin, and anogenital cancer, …

Structural features of intra-and intermolecular G-quadruplexes derived from telomeric repeats

V Víglaský, L Bauer, K Tlučková - Biochemistry, 2010 - ACS Publications
The 3′ strand of telomeres is composed of tandem repeats of short G-rich sequences which
protrude as single-stranded DNA overhangs. These repeats are G 3 T 2 A in humans and G …

The circular dichroism and differential scanning calorimetry study of the properties of DNA aptamer dimers

S Poniková, K Tlučková, M Antalík, V Víglaský… - Biophysical …, 2011 - Elsevier
We have applied circular dichroism (CD), temperature-gradient gel electrophoresis (TGGE)
and differential scanning calorimetry (DSC) to study the properties of novel bioengineered …

G-quadruplex motifs arranged in tandem occurring in telomeric repeats and the insulin-linked polymorphic region

L Bauer, K Tlučková, P Tóthová, V Viglaský - Biochemistry, 2011 - ACS Publications
To date, various G-quadruplex structures have been reported in the human genome. There
are numerous studies focusing on quadruplex-forming sequences in general, but few studies …

The first derivative of a function of circular dichroism spectra: biophysical study of human telomeric G-quadruplex

V Víglaský, K Tlučková, Ľ Bauer - European Biophysics Journal, 2011 - Springer
Depending on conditions and base modifications, telomeric repeats can form many
topological structures; parallel, antiparallel and hybrid forms. The influence of salts and some …

The human RNA polymerase I structure reveals an HMG-like docking domain specific to metazoans

…, EP Ramsay, K Tlučková… - Life Science …, 2022 - life-science-alliance.org
Transcription of the ribosomal RNA precursor by RNA polymerase (Pol) I is a major
determinant of cellular growth, and dysregulation is observed in many cancer types. Here, we …

[HTML][HTML] Telomeric G-Quadruplexes: From Human to Tetrahymena Repeats

…, Ľ Bauer, P Krafčíková, K Tlučková… - Journal of Nucleic …, 2017 - hindawi.com
The human telomeric and protozoal telomeric sequences differ only in one purine base in
their repeats; TTAGGG in telomeric sequences; and TTGGGG in protozoal sequences. In this …

[HTML][HTML] Evaluation of human telomeric G-quadruplexes: the influence of overhanging sequences on quadruplex stability and folding

V Viglasky, L Bauer, K Tluckova, P Javorsky - Journal of nucleic acids, 2010 - hindawi.com
To date, various G-quadruplex structures have been reported in human telomeric sequences.
Human telomeric repeats can form many topological structures depending on conditions …

Mechanism of mammalian transcriptional repression by noncoding RNA

K Tluckova, AP Testa Salmazo, CA Bernecky - 2023 - research-explorer.ista.ac.at
Transcription by RNA polymerase II (Pol II) can be repressed by noncoding RNA, including
the human RNA Alu. However, the mechanism by which endogenous RNAs repress …

The human RNA polymerase I structure reveals an HMG-like transcription factor docking domain specific to metazoans

…, FB Heiss, G Abascal-Palacios, E Ramsay, K Tlučková… - bioRxiv, 2021 - biorxiv.org
Transcription of the ribosomal RNA precursor by RNA polymerase (Pol) I is a major determinant
of cellular growth and dysregulation is observed in many cancer types. Here, we present …