User profiles for Jorge L Rodriguez-Gil

Jorge L. Rodriguez-Gil MD-DPhil

Stanford University School of Medicine
Verified email at stanford.edu
Cited by 2863

The landscape of recombination in African Americans

…, BM Psaty, AP Reiner, SS Rich, JL Rodriguez-Gil… - Nature, 2011 - nature.com
Recombination, together with mutation, gives rise to genetic variation in populations. Here we
leverage the recent mixture of people of African and European ancestry in the Americas to …

A common variant at the TERT-CLPTM1L locus is associated with estrogen receptor–negative breast cancer

…, TR Rebbeck, JL Rodriguez-Gil, L Rosenberg… - Nature …, 2011 - nature.com
Estrogen receptor (ER)-negative breast cancer shows a higher incidence in women of African
ancestry compared to women of European ancestry. In search of common risk alleles for …

A meta-analysis identifies new loci associated with body mass index in individuals of African ancestry

…, LJ Rasmussen-Torvik, JL Rodriguez-Gil… - Nature …, 2013 - nature.com
Genome-wide association studies (GWAS) have identified 36 loci associated with body mass
index (BMI), predominantly in populations of European ancestry. We conducted a meta-…

A meta-analysis of genome-wide association studies of breast cancer identifies two novel susceptibility loci at 6q14 and 20q11

…, SM Gerty, JL Rodriguez-Gil… - Human molecular …, 2012 - academic.oup.com
Genome-wide association studies (GWAS) of breast cancer defined by hormone receptor
status have revealed loci contributing to susceptibility of estrogen receptor (ER)-negative …

[HTML][HTML] Enhanced statistical tests for GWAS in admixed populations: assessment using African Americans from CARe and a Breast Cancer Consortium

…, SJ Chanock, SL Deming, JL Rodriguez-Gil… - PLoS …, 2011 - journals.plos.org
While genome-wide association studies (GWAS) have primarily examined populations of
European ancestry, more recent studies often involve additional populations, including …

[HTML][HTML] Identification, replication, and fine-mapping of Loci associated with adult height in individuals of african ancestry

…, MF Press, S Redline, JL Rodriguez-Gil… - PLoS …, 2011 - journals.plos.org
Adult height is a classic polygenic trait of high heritability (h 2 ∼0.8). More than 180 single
nucleotide polymorphisms (SNPs), identified mostly in populations of European descent, are …

[PDF][PDF] Genome-wide scan of 29,141 African Americans finds no evidence of directional selection since admixture

…, S Nyante, MF Press, JL Rodriguez-Gil… - The American Journal of …, 2014 - cell.com
The extent of recent selection in admixed populations is currently an unresolved question.
We scanned the genomes of 29,141 African Americans and failed to find any genome-wide-…

A genome-wide association study of breast cancer in women of African ancestry

…, EA Ruiz-Narvaez, SL Deming, JL Rodriguez-Gil… - Human genetics, 2013 - Springer
Genome-wide association studies (GWAS) in diverse populations are needed to reveal
variants that are more common and/or limited to defined populations. We conducted a GWAS of …

Genome-wide association studies in women of African ancestry identified 3q26. 21 as a novel susceptibility locus for oestrogen receptor negative breast cancer

…, MF Press, SL Deming, JL Rodriguez-Gil… - Human molecular …, 2016 - academic.oup.com
Multiple breast cancer loci have been identified in previous genome-wide association studies,
but they were mainly conducted in populations of European ancestry. Women of African …

[HTML][HTML] Cross-ancestry GWAS meta-analysis identifies six breast cancer loci in African and European ancestry women

…, SL Deming-Halverson, JL Rodriguez-Gil… - Nature …, 2021 - nature.com
Our study describes breast cancer risk loci using a cross-ancestry GWAS approach. We first
identify variants that are associated with breast cancer at P < 0.05 from African ancestry …