User profiles for Jonathan J Chang

Jonathan Chang

Graduate Student, Georgia Institute of Technology
Verified email at gatech.edu
Cited by 174

[HTML][HTML] Stromal PDGFR-α activation enhances matrix stiffness, impedes mammary ductal development, and accelerates tumor growth

…, VC Shukla, A Avendano, ST Sizemore, JJ Chang… - Neoplasia, 2017 - Elsevier
The extracellular matrix (ECM) is critical for mammary ductal development and differentiation,
but how mammary fibroblasts regulate ECM remodeling remains to be elucidated. Herein, …

Integrated biophysical characterization of fibrillar collagen-based hydrogels

A Avendano, JJ Chang… - ACS biomaterials …, 2020 - ACS Publications
This paper describes an experimental characterization scheme of the biophysical properties
of reconstituted hydrogel matrices based on indentation testing, quantification of transport …

[HTML][HTML] The spatial and temporal domains of modern ecology

…, T Treuer, L Ahmed, K Caylor, J Chang… - Nature ecology & …, 2018 - nature.com
To understand ecological phenomena, it is necessary to observe their behaviour across
multiple spatial and temporal scales. Since this need was first highlighted in the 1980s, …

[HTML][HTML] A mathematical model of the metabolic and perfusion effects on cortical spreading depression

JC Chang, KC Brennan, D He, H Huang, RM Miura… - PLoS …, 2013 - journals.plos.org
Cortical spreading depression (CSD) is a slow-moving ionic and metabolic disturbance that
propagates in cortical brain tissue. In addition to massive cellular depolarizations, CSD also …

PF-07059013: a noncovalent modulator of hemoglobin for treatment of sickle cell disease

…, A Casimiro-Garcia, JS Chang… - Journal of Medicinal …, 2020 - ACS Publications
Sickle cell disease (SCD) is a genetic disorder caused by a single point mutation (β6 Glu →
Val) on the β-chain of adult hemoglobin (HbA) that results in sickled hemoglobin (HbS). In …

Flexor tendon tissue engineering: bioreactor cyclic strain increases construct strength

…, RL Smith, J Riboh, H Pham, J Chang - … Engineering Part A, 2010 - liebertpub.com
… Bates SJChang J.A comparison of tenocytes and mesenchymal stem cells for use in flexor
tendon tissue engineeringJ Hand Surg325972007. 12. Kryger, GS, Chong, AKS, Costa, M., …

Strengthening health systems while responding to a health crisis: lessons learned by a nongovernmental organization during the Ebola virus disease epidemic in …

…, C Nally, S James, GS Warren, J Chang… - The Journal of …, 2016 - academic.oup.com
An epidemic of Ebola virus disease (EVD) beginning in 2013 has claimed an estimated 11
310 lives in West Africa. As the EVD epidemic subsides, it is important for all who participated …

Production of biosurfactants from agro-industrial waste and waste cooking oil in a circular bioeconomy: An overview

…, R Sirohi, S Varjani, MJ Taherzadeh, JS Chang… - Bioresource …, 2022 - Elsevier
Waste generation is becoming a global concern owing to its adverse effects on environment
and human health. The utilization of waste as a feedstock for production of value-added …

Enhanced CAR–T cell activity against solid tumors by vaccine boosting through the chimeric receptor

L Ma, T Dichwalkar, JYH Chang, B Cossette… - Science, 2019 - science.org
Chimeric antigen receptor–T cell (CAR-T) therapy has been effective in the treatment of
hematologic malignancies, but it has shown limited efficacy against solid tumors. Here we …

Subterfuge and manipulation: type III effector proteins of phytopathogenic bacteria

SR Grant, EJ Fisher, JH Chang, BM Mole… - Annu. Rev …, 2006 - annualreviews.org
Diverse gram-negative bacteria deliver effector proteins into the cells of their eukaryotic hosts
using the type III secretion system. Collectively, these type III effector proteins function to …