User profiles for Jonathan Florentin

jonathan florentin

Medical College of Wisconsin
Verified email at mcw.edu
Cited by 825

[PDF][PDF] HRas signal transduction promotes hepatitis C virus cell entry by triggering assembly of the host tetraspanin receptor complex

…, C Thumann, HJ Harris, A Barnes, J Florentin… - Cell host & …, 2013 - cell.com
Hepatitis C virus (HCV) entry is dependent on coreceptor complex formation between the
tetraspanin superfamily member CD81 and the tight junction protein claudin-1 (CLDN1) on the …

Sargassum seaweed on Caribbean islands: an international public health concern

…, R Banydeen, P Gueye, J Florentin… - Lancet (London …, 2019 - pubmed.ncbi.nlm.nih.gov
… 2 , Jonathan Florentin

Inflammatory macrophage expansion in pulmonary hypertension depends upon mobilization of blood-borne monocytes

J Florentin, E Coppin, SB Vasamsetti… - The Journal of …, 2018 - journals.aai.org
Pulmonary inflammation, which is characterized by the presence of perivascular macrophages,
has been proposed as a key pathogenic driver of pulmonary hypertension (PH), a …

[PDF][PDF] Sympathetic neuronal activation triggers myeloid progenitor proliferation and differentiation

SB Vasamsetti, J Florentin, E Coppin, LCA Stiekema… - Immunity, 2018 - cell.com
There is a growing body of research on the neural control of immunity and inflammation.
However, it is not known whether the nervous system can regulate the production of …

Interleukin-6 mediates neutrophil mobilization from bone marrow in pulmonary hypertension

J Florentin, J Zhao, YY Tai, SB Vasamsetti… - Cellular & molecular …, 2021 - nature.com
Myeloid cells, such as neutrophils, are produced in the bone marrow in high quantities and
are important in the pathogenesis of vascular diseases such as pulmonary hypertension (PH)…

Modification of host dendritic cells by microchimerism-derived extracellular vesicles generates split tolerance

W Bracamonte-Baran, J Florentin… - Proceedings of the …, 2017 - National Acad Sciences
Maternal microchimerism (MMc) has been associated with development of allospecific
transplant tolerance, antitumor immunity, and cross-generational reproductive fitness, but its …

Regulation of cardiovascular health and disease by visceral adipose tissue‐derived metabolic hormones

…, N Natarajan, S Sadaf, J Florentin… - The Journal of …, 2023 - Wiley Online Library
Visceral adipose tissue (VAT) is a metabolic organ known to regulate fat mass, and glucose
and nutrient homeostasis. VAT is an active endocrine gland that synthesizes and secretes …

Sargassum seaweed health menace in the Caribbean: clinical characteristics of a population exposed to hydrogen sulfide during the 2018 massive stranding

D Resiere, H Mehdaoui, J Florentin, P Gueye… - Clinical …, 2021 - Taylor & Francis
Background Since 2011, there have been ongoing massive unexplained increases of sargassum
seaweed strandings along the coastlines of Caribbean countries. The objective of our …

HCV glycoprotein E2 is a novel BDCA-2 ligand and acts as an inhibitor of IFN production by plasmacytoid dendritic cells

J Florentin, B Aouar, C Dental… - Blood, The Journal …, 2012 - ashpublications.org
The elimination of hepatitis C virus (HCV) in > 50% of chronically infected patients by treatment
with IFN-α suggests that plasmacytoid dendritic cells (pDCs), major producers of IFN-α, …

Long range endocrine delivery of circulating miR-210 to endothelium promotes pulmonary hypertension

J Zhao, J Florentin, YY Tai, S Torrino, L Ohayon… - Circulation …, 2020 - Am Heart Assoc
Rationale: Unproven theories abound regarding the long-range uptake and endocrine
activity of extracellular blood-borne microRNAs into tissue. In pulmonary hypertension (PH), …