User profiles for Jeremy M Boss
Jeremy M. BossProfessor of Microbiology & Immunology, Emory University Verified email at emory.edu Cited by 20934 |
The role of innate and adaptive immunity in Parkinson's disease
GT Kannarkat, JM Boss… - Journal of Parkinson's …, 2013 - content.iospress.com
In recent years, inflammation has become implicated as a major pathogenic factor in the onset
and progression of Parkinson's disease. Understanding the precise role for inflammation …
and progression of Parkinson's disease. Understanding the precise role for inflammation …
Genetic and epigenetic regulation of PD-1 expression
APR Bally, JW Austin, JM Boss - The Journal of Immunology, 2016 - journals.aai.org
The inhibitory immune receptor programmed cell death-1 (PD-1) is intricately regulated. In T
cells, PD-1 is expressed in response to most immune challenges, but it is rapidly …
cells, PD-1 is expressed in response to most immune challenges, but it is rapidly …
Regulation of transcription of MHC class II genes
JM Boss - Current opinion in immunology, 1997 - Elsevier
Genetic and biochemical analyses have identified multiple DNA-binding and non-DNA-binding
proteins that functionally regulate MHC class II genes. These include RFX, X2BP, NF-Y, …
proteins that functionally regulate MHC class II genes. These include RFX, X2BP, NF-Y, …
[PDF][PDF] The NLR gene family: a standard nomenclature
Immune regulatory proteins such as CIITA, NAIP, IPAF, NOD1, NOD2, NALP1, and cryopyrin
(also known as NALP3) are members of a family characterized by the presence of a NACHT …
(also known as NALP3) are members of a family characterized by the presence of a NACHT …
The neuron-specific protein PGP 9.5 is a ubiquitin carboxyl-terminal hydrolase
…, K Lee, S Deshpande, P Duerksen-Hughes, JM Boss… - Science, 1989 - science.org
A complementary DNA (cDNA) for ubiquitin carboxyl-terminal hydrolase isozyme L3 was
cloned from human B cells. The cDNA encodes a protein of 230 amino acids with a molecular …
cloned from human B cells. The cDNA encodes a protein of 230 amino acids with a molecular …
[HTML][HTML] Defining the CREB regulon: a genome-wide analysis of transcription factor regulatory regions
…, H Cha-Molstad, JM Dwyer, GS Yochum, JM Boss… - Cell, 2004 - cell.com
The CREB transcription factor regulates differentiation, survival, and synaptic plasticity. The
complement of CREB targets responsible for these responses has not been identified, …
complement of CREB targets responsible for these responses has not been identified, …
Immune interferon activates multiple class II major histocompatibility complex genes and the associated invariant chain gene in human endothelial cells and dermal …
…, AJ Korman, CT Wake, JM Boss… - Proceedings of the …, 1984 - National Acad Sciences
Immune interferon (IFN-gamma) increases the surface expression of HLA-A,B antigens and
induces the surface expression of HLA-DR antigens on vascular endothelial cells and …
induces the surface expression of HLA-DR antigens on vascular endothelial cells and …
[PDF][PDF] Distinct effector B cells induced by unregulated toll-like receptor 7 contribute to pathogenic responses in systemic lupus erythematosus
Systemic Lupus Erythematosus (SLE) is characterized by B cells lacking IgD and CD27 (double
negative; DN). We show that DN cell expansions reflected a subset of CXCR5 - CD11c + …
negative; DN). We show that DN cell expansions reflected a subset of CXCR5 - CD11c + …
Transcription factor T-bet represses expression of the inhibitory receptor PD-1 and sustains virus-specific CD8+ T cell responses during chronic infection
…, JM Angelosanto, MAA Ali, AM Intlekofer, JM Boss… - Nature …, 2011 - nature.com
T cell exhaustion has a major role in failure to control chronic infection. High expression of
inhibitory receptors, including PD-1, and the inability to sustain functional T cell responses …
inhibitory receptors, including PD-1, and the inability to sustain functional T cell responses …
NFATc1 regulates PD-1 expression upon T cell activation
PD-1 is a transmembrane protein involved in the regulation of immunological tolerance.
Multiple studies have reported an association between high levels of PD-1 expressed on T cell …
Multiple studies have reported an association between high levels of PD-1 expressed on T cell …