m6A in mRNA: an ancient mechanism for fine-tuning gene expression
JY Roignant, M Soller - Trends in Genetics, 2017 - cell.com
Modifications in mRNA constitute ancient mechanisms to regulate gene expression post-transcriptionally.
N 6 -methyladenosine (m 6 A) is the most prominent mRNA modification, and …
N 6 -methyladenosine (m 6 A) is the most prominent mRNA modification, and …
m6A modulates neuronal functions and sex determination in Drosophila
…, MA Andrade-Navarro, B Poeck, M Helm, JY Roignant - Nature, 2016 - nature.com
N 6 -methyladenosine RNA (m 6 A) is a prevalent messenger RNA modification in vertebrates.
Although its functions in the regulation of post-transcriptional gene expression are …
Although its functions in the regulation of post-transcriptional gene expression are …
[HTML][HTML] Quantifying post-transcriptional regulation in the development of Drosophila melanogaster
Even though proteins are produced from mRNA, the correlation between mRNA levels and
protein abundances is moderate in most studies, occasionally attributed to complex post-…
protein abundances is moderate in most studies, occasionally attributed to complex post-…
[HTML][HTML] Pattern formation in the Drosophila eye disc
JY Roignant, JE Treisman - The International journal of …, 2009 - ncbi.nlm.nih.gov
Differentiation of the Drosophila compound eye from the eye imaginal disc is a progressive
process: columns of cells successively differentiate in a posterior to anterior sequence, …
process: columns of cells successively differentiate in a posterior to anterior sequence, …
[HTML][HTML] Anything but ordinary–emerging splicing mechanisms in eukaryotic gene regulation
NH Gehring, JY Roignant - Trends in Genetics, 2021 - cell.com
Splicing of precursor mRNAs (pre-mRNA) is an important step during eukaryotic gene
expression. The identification of the actual splice sites and the proper removal of introns are …
expression. The identification of the actual splice sites and the proper removal of introns are …
Zc3h13/Flacc is required for adenosine methylation by bridging the mRNA-binding factor Rbm15/Spenito to the m6A machinery component Wtap/Fl (2) d
N 6-methyladenosine (m 6 A) is the most abundant mRNA modification in eukaryotes,
playing crucial roles in multiple biological processes. m 6 A is catalyzed by the activity of …
playing crucial roles in multiple biological processes. m 6 A is catalyzed by the activity of …
Absence of transitive and systemic pathways allows cell-specific and isoform-specific RNAi in Drosophila
JY Roignant, C Carré, B Mugat, D Szymczak… - Rna, 2003 - rnajournal.cshlp.org
RNA interference (RNAi) designates the multistep process by which double-stranded RNA
induces the silencing of homologous endogenous genes. Some aspects of RNAi appear to …
induces the silencing of homologous endogenous genes. Some aspects of RNAi appear to …
[HTML][HTML] Hakai is required for stabilization of core components of the m6A mRNA methylation machinery
N 6 -methyladenosine (m 6 A) is the most abundant internal modification on mRNA which
influences most steps of mRNA metabolism and is involved in several biological functions. The …
influences most steps of mRNA metabolism and is involved in several biological functions. The …
The developmental proteome of Drosophila melanogaster
…, D Kappei, B Altenhein, JY Roignant… - Genome …, 2017 - genome.cshlp.org
Drosophila melanogaster is a widely used genetic model organism in developmental
biology. While this model organism has been intensively studied at the RNA level, a …
biology. While this model organism has been intensively studied at the RNA level, a …
Ythdf is a N6‐methyladenosine reader that modulates Fmr1 target mRNA selection and restricts axonal growth in Drosophila
…, A Quattrone, A Soldano, JY Roignant - The EMBO …, 2021 - embopress.org
N6‐methyladenosine (m 6 A) regulates a variety of physiological processes through modulation
of RNA metabolism. This modification is particularly enriched in the nervous system of …
of RNA metabolism. This modification is particularly enriched in the nervous system of …