[HTML][HTML] PAR-CLIP analysis uncovers AUF1 impact on target RNA fate and genome integrity
Post-transcriptional gene regulation is robustly regulated by RNA-binding proteins (RBPs).
Here we describe the collection of RNAs regulated by AUF1 (AU-binding factor 1), an RBP …
Here we describe the collection of RNAs regulated by AUF1 (AU-binding factor 1), an RBP …
[HTML][HTML] Scaffold function of long non-coding RNA HOTAIR in protein ubiquitination
JH Yoon, K Abdelmohsen, J Kim, X Yang… - Nature …, 2013 - nature.com
Although mammalian long non-coding (lnc)RNAs are best known for modulating transcription,
their post-transcriptional influence on mRNA splicing, stability and translation is emerging. …
their post-transcriptional influence on mRNA splicing, stability and translation is emerging. …
[PDF][PDF] LincRNA-p21 suppresses target mRNA translation
JH Yoon, K Abdelmohsen, S Srikantan, X Yang… - Molecular cell, 2012 - cell.com
Mammalian long intergenic noncoding RNAs (lincRNAs) are best known for modulating
transcription. Here we report a posttranscriptional function for lincRNA-p21 as a modulator of …
transcription. Here we report a posttranscriptional function for lincRNA-p21 as a modulator of …
[PDF][PDF] NEAT1 is essential for metabolic changes that promote breast cancer growth and metastasis
Accelerated glycolysis is the main metabolic change observed in cancer, but the underlying
molecular mechanisms and their role in cancer progression remain poorly understood. Here…
molecular mechanisms and their role in cancer progression remain poorly understood. Here…
Posttranscriptional gene regulation by long noncoding RNA
JH Yoon, K Abdelmohsen, M Gorospe - Journal of molecular biology, 2013 - Elsevier
Eukaryotic cells transcribe a vast number of noncoding RNA species. Among them, long
noncoding RNAs (lncRNAs) have been widely implicated in the regulation of gene transcription. …
noncoding RNAs (lncRNAs) have been widely implicated in the regulation of gene transcription. …
Functional interactions among microRNAs and long noncoding RNAs
JH Yoon, K Abdelmohsen, M Gorospe - Seminars in cell & developmental …, 2014 - Elsevier
In mammals, the vast majority of transcripts expressed are noncoding RNAs, ranging from
short RNAs (including microRNAs) to long RNAs spanning up to hundreds of kb. While the …
short RNAs (including microRNAs) to long RNAs spanning up to hundreds of kb. While the …
Stress-specific composition, assembly and kinetics of stress granules in Saccharomyces cerevisiae
Eukaryotic cells respond to cellular stresses by the inhibition of translation and the accumulation
of mRNAs in cytoplasmic RNA–protein (ribonucleoprotein) granules termed stress …
of mRNAs in cytoplasmic RNA–protein (ribonucleoprotein) granules termed stress …
Senescence‐associated l nc RNA s: senescence‐associated long noncoding RNA s
Noncoding RNA s include small transcripts, such as micro RNA s and piwi‐interacting RNA
s, and a wide range of long noncoding RNA s (lnc RNA s). Although many lnc RNA s have …
s, and a wide range of long noncoding RNA s (lnc RNA s). Although many lnc RNA s have …
HuR and GRSF1 modulate the nuclear export and mitochondrial localization of the lncRNA RMRP
Some mitochondrial long noncoding RNAs (lncRNAs) are encoded by nuclear DNA, but the
mechanisms that mediate their transport to mitochondria are poorly characterized. Using …
mechanisms that mediate their transport to mitochondria are poorly characterized. Using …
MicroRNA 33 regulates glucose metabolism
…, L Goedeke, N Rotllan, JH Yoon… - … and cellular biology, 2013 - Taylor & Francis
Metabolic diseases are characterized by the failure of regulatory genes or proteins to effectively
orchestrate specific pathways involved in the control of many biological processes. In …
orchestrate specific pathways involved in the control of many biological processes. In …