Although viruses are simple in structure and composition, their interactions with host cells
are complex. Merely to gain entry, animal viruses make use of a repertoire of cellular …

As opportunistic pathogens, viruses have evolved many elegant strategies to manipulate
host cells for infectious entry and replication. Viral apoptotic mimicry, defined by the exposure …

Many cellular responses are triggered by proteins, drugs or pathogens binding to cell-surface
receptors, but it can be challenging to identify which receptors are bound by a given ligand…

Vaccinia virus (VACV), the model poxvirus, produces two types of infectious particles: mature
virions (MVs) and extracellular virions (EVs). EV particles possess two membranes and …

To achieve efficient binding and subsequent fusion, most enveloped viruses encode between
one and five proteins 1 . For many viruses, the clustering of fusion proteins—and their …

Viruses employ many different strategies to enter host cells. Vaccinia virus, a prototype poxvirus,
enters cells in a pH-dependent fashion. Live cell imaging showed that fluorescent virus …

As obligatory intracellular parasites, viruses rely on host-cell functions for most aspects of
their replication cycle. This is born out during entry, when most viruses that infect vertebrate …

The molecular nature of store-operated Ca 2+ -selective channels has remained an enigma,
due largely to the continued inability to convincingly demonstrate Ca 2+ -selective store-…

… Jason C. Mercer… Mercer …

Super-resolution microscopy depends on steps that can contribute to the formation of image
artifacts, leading to misinterpretation of biological information. We present NanoJ-…