Genetic coessentiality analysis, a computational approach which identifies genes sharing a
common effect on cell fitness across large-scale screening datasets, has emerged as a …

The interrelated programs essential for cellular fitness in the face of stress are critical to
understanding tumorigenesis, neurodegeneration, and aging. However, modelling the …

Chemical-genetic interaction profiling in model organisms has proven powerful in providing
insights into compound mechanism of action and gene function. However, identifying …

Chemical-genetic interaction profiling in model organisms has proven powerful in providing
insights into compound mechanism of action and gene function. However, identifying …

Homophily, the tendency of people to associate with others similar to themselves, is observed
in many social networks, ranging from friendships to marriages to business relationships, …

Rare high- 3 He/ 4 He signatures in ocean island basalts (OIB) erupted at volcanic hotspots
derive from deep-seated domains preserved in Earth’s interior. Only high- 3 He/ 4 He OIB …

NF-κB, a central coordinator of immune and inflammatory responses, must be tightly regulated.
We describe a NF-κB regulatory pathway that is driven by reversible lysine methylation of …

We examine different populations’ play in coordination games in online experiments with
over 1,000 study participants. Study participants played a two-player coordination game that …

Chlorhexidine is widely used as an antiseptic or disinfectant in both hospital and community
settings. A number of bacterial species display resistance to this membrane-active biocide. …

The noble gas isotope systematics of ocean island basalts suggest the existence of primordial
mantle signatures in the deep mantle. Yet, the isotopic compositions of lithophile elements …