Germline-specific Piwi-interacting RNAs (piRNAs) protect animal genomes against transposons
and are essential for fertility. piRNAs targeting active transposons are amplified by the …

Viral fusion proteins mediate the merger of host and viral membranes during cell entry for all
enveloped viruses. Baculovirus glycoprotein gp64 (gp64) is unusual in promoting entry into …

Nonsense-mediated mRNA decay (NMD) is a surveillance mechanism by which eukaryotic
cells detect and degrade transcripts containing premature termination codons. Three 'up-…

Here, we report the biochemical characterization of the nonspecific lethal (NSL) complex (NSL1,
NSL2, NSL3, MCRS2, MBD-R2, and WDS) that associates with the histone …

Nonsense‐mediated decay (NMD) is a eukaryotic quality control mechanism that degrades
mRNAs carrying premature stop codons. In mammalian cells, NMD is triggered when UPF2 …

The subunits of the nonspecific lethal (NSL) complex, which include the histone acetyltransferase
MOF (males absent on the first), play important roles in various cellular functions, …

PRDM9, a histone lysine methyltransferase, is a key determinant of the localization of meiotic
recombination hot spots in humans and mice and the only vertebrate protein known to be …

The programmed formation of hundreds of DNA double-strand breaks (DSBs) is essential for
proper meiosis and fertility. In mice and humans, the location of these breaks is determined …

Dehydration of protein crystals is rarely used, despite being a post-crystallization method
that is useful for the improvement of crystal diffraction properties, as it is difficult to reproduce …

Nerve terminals release neurotransmitters from vesicles into the synaptic cleft upon transient
increases in intracellular Ca 2+ . This exocytotic process requires the formation of trans …