User profiles for Ioannis S Pateras
Ioannis PaterasNational and Kapodistrian University of Athens, Medical School, Athens, Greece Verified email at med.uoa.gr Cited by 3611 |
[PDF][PDF] Mutant p53 prolongs NF-κB activation and promotes chronic inflammation and inflammation-associated colorectal cancer
…, IS Pateras, O Tarcic, H Solomon, AJ Schetter, S Wilder… - Cancer cell, 2013 - cell.com
The tumor suppressor p53 is frequently mutated in human cancer. Common mutant p53 (mutp53)
isoforms can actively promote cancer through gain-of-function (GOF) mechanisms. We …
isoforms can actively promote cancer through gain-of-function (GOF) mechanisms. We …
[HTML][HTML] Mutant p53 cancers reprogram macrophages to tumor supporting macrophages via exosomal miR-1246
T Cooks, IS Pateras, LM Jenkins, KM Patel… - Nature …, 2018 - nature.com
TP53 mutants (mutp53) are involved in the pathogenesis of most human cancers. Specific
mutp53 proteins gain oncogenic functions (GOFs) distinct from the tumor suppressor activity of …
mutp53 proteins gain oncogenic functions (GOFs) distinct from the tumor suppressor activity of …
[PDF][PDF] Dual function of p38α MAPK in colon cancer: suppression of colitis-associated tumor initiation but requirement for cancer cell survival
Colorectal cancer is frequently associated with chronic inflammation, with the intestinal
epithelial barrier playing an important protective role against the infections and injuries that …
epithelial barrier playing an important protective role against the infections and injuries that …
p57KIP2: “Kip”ing the Cell under Control
IS Pateras, K Apostolopoulou, K Niforou… - Molecular Cancer …, 2009 - AACR
… oscillations of G and S phases in the … S-entry and reappearing after the completion of S
phase (115). Introduction of a stable form of p57 KIP2 into trophoblast giant cells blocks G1- to S-…
phase (115). Introduction of a stable form of p57 KIP2 into trophoblast giant cells blocks G1- to S-…
The DNA damage response and immune signaling alliance: Is it good or bad? Nature decides when and where
IS Pateras, S Havaki, X Nikitopoulou, K Vougas… - Pharmacology & …, 2015 - Elsevier
The characteristic feature of healthy living organisms is the preservation of homeostasis.
Compelling evidence highlight that the DNA damage response and repair (DDR/R) and …
Compelling evidence highlight that the DNA damage response and repair (DDR/R) and …
[PDF][PDF] RNF20 links histone H2B ubiquitylation with inflammation and inflammation-associated cancer
Factors linking inflammation and cancer are of great interest. We now report that the
chromatin-targeting E3 ubiquitin ligase RNF20/RNF40, driving histone H2B monoubiquitylation (…
chromatin-targeting E3 ubiquitin ligase RNF20/RNF40, driving histone H2B monoubiquitylation (…
Functional interplay between the DNA-damage-response kinase ATM and ARF tumour suppressor protein in human cancer
…, A Dereli-Oz, M Kocylowski, IS Pateras… - Nature cell …, 2013 - nature.com
The DNA damage response (DDR) pathway and ARF function as barriers to cancer development.
Although commonly regarded as operating independently of each other, some studies …
Although commonly regarded as operating independently of each other, some studies …
Integrating the DNA damage and protein stress responses during cancer development and treatment
… Ioannis S Pateras … Ioannis S Pateras … proximal pausing sites maximizes sensing and
accelerates the repair of category-S lesions equally well in genes with low and high expression via …
accelerates the repair of category-S lesions equally well in genes with low and high expression via …
[HTML][HTML] Mutant p53 gain of function underlies high expression levels of colorectal cancer stem cells markers
H Solomon, N Dinowitz, IS Pateras, T Cooks, Y Shetzer… - Oncogene, 2018 - nature.com
Emerging notion in carcinogenesis ascribes tumor initiation and aggressiveness to cancer
stem cells (CSCs). Specifically, colorectal cancer (CRC) development was shown to be …
stem cells (CSCs). Specifically, colorectal cancer (CRC) development was shown to be …
[HTML][HTML] Inflammation, DNA damage, Helicobacter pylori and gastric tumorigenesis
P Kalisperati, E Spanou, IS Pateras… - Frontiers in …, 2017 - frontiersin.org
Helicobacter pylori (H. pylori) is a Gram negative bacterium that colonizes the stomach of
almost half human population. It has evolved to escape immune surveillance, establishes …
almost half human population. It has evolved to escape immune surveillance, establishes …