Background Valproic acid (VPA), a commonly used mood stabilizer that promotes neuronal
differentiation, regulates multiple signaling pathways involving extracellular signal-regulated …

Background Alopecia is the common hair loss problem that can affect many people. However,
current therapies for treatment of alopecia are limited by low efficacy and potentially …

Both the Wnt/β-catenin and Ras pathways are aberrantly activated in most human colorectal
cancers (CRCs) and interact cooperatively in tumor promotion. Inhibition of these signaling …

Obesity, which is related to metabolic syndrome and is associated with liver disease, represents
an epidemic problem demanding effective therapeutic strategies. Evidence shows that …

The external epithelial surfaces of plants and animals are frequently carpeted with small
micro- and nanostructures, which broadens their adaptive capabilities in challenging physical …

Wnt/β-catenin signaling plays important roles in cutaneous wound healing and dermal
fibrosis. However, its regulatory mechanism has not been fully elucidated, and a commercially …

Background Small cell lung cancer (SCLC) has an exceptionally poor prognosis; as most of
the cases are initially diagnosed as extensive disease with hematogenous metastasis. …

CXXC5 is a member of a small subset of proteins containing CXXC‐type zinc‐finger domain.
Here, we show that CXXC5 is a transcription factor activating Flk‐1, a receptor for vascular …

Background Natural products can serve as one of the alternatives, exhibiting high potential
for the treatment and prevention of COVID-19, caused by SARS-CoV-2. Herein, we report a …

Taste stem/progenitor cells from posterior mouse tongues have been used to generate taste
bud organoids. However, the inaccessible location of taste receptor cells is observed in …