Despite growing interest and a recent surge in papers, the role of autophagy in glucose and
lipid metabolism is unclear. We produced mice with skeletal muscle–specific deletion of …

Background. Although neutrophils and T cells are important in mediating renal injury
following ischaemia/reperfusion, the role of macrophages is still unknown. Using liposomal …

Background. Ischaemia/reperfusion is a major cause of acute kidney injury and can result in
poor long-term graft function. Although most of the patients with acute kidney injury recover …

… panel Sang-Kyung Jo , Won Yong Cho , Su Ah Sung , Hyoung Kyu Kim , Nam Hee Won …
HW Kim, Mrs. YS Ko, and Mrs. KH Chang for their excellent technical supports during the …

Aldosterone induces myocardial fibrosis and vascular inflammation via proinflammatory and
profibrotic cytokines. The effect of spironolactone on renal inflammation and renal function …

… Author links open overlay panel Dae Ryong Cha MD , Nan Hee Kim , Jong Woo Yoon , Sang
Kyung Jo , Won Yong Cho , Hyoung Kyu Kim , Nam Hee Won … Kim, D. Atluru, WF Keane …

Background. Peroxisome proliferator-activated receptors (PPARs) are nuclear transcription
factors that play a role in insulin sensitivity, lipid metabolism and inflammation. However, the …

Alternative splicing (AS) of protein-coding messenger RNAs is an essential regulatory
mechanism in eukaryotic gene expression that controls the proper function of proteins. It is also …

Tamoxifen resistance is often observed in the majority of estrogen receptor–positive breast
cancers and it remains as a serious clinical problem in breast cancer management. …

Chemokine ligand 2 (CCL2) binds to its receptor C–C chemokine receptor 2 (CCR2), initiating
tissue inflammation, and recent studies have suggested a beneficial effect of a blockade …