PTEN/MMAC1/TEP1 suppresses the tumorigenicity and induces G1 cell cycle arrest in human glioblastoma cells
DM Li, H Sun - Proceedings of the National Academy of …, 1998 - National Acad Sciences
PTEN/MMAC1/TEP1 is a tumor suppressor that possesses intrinsic phosphatase activity.
Deletions or mutations of its encoding gene are associated with a variety of human cancers. …
Deletions or mutations of its encoding gene are associated with a variety of human cancers. …
MKP-1 (3CH134), an immediate early gene product, is a dual specificity phosphatase that dephosphorylates MAP kinase in vivo
H Sun, CH Charles, LF Lau, NK Tonks - Cell, 1993 - cell.com
Mitogenic stimulation of cells induces rapid and transient activation of MAP kinases. Here
we repot-l that a growth factor-inducible gene, 3CH134, encodes a dual specificity …
we repot-l that a growth factor-inducible gene, 3CH134, encodes a dual specificity …
IDF Diabetes Atlas: Global, regional and country-level diabetes prevalence estimates for 2021 and projections for 2045
H Sun, P Saeedi, S Karuranga, M Pinkepank… - Diabetes research and …, 2022 - Elsevier
Aims To provide global, regional, and country-level estimates of diabetes prevalence and
health expenditures for 2021 and projections for 2045. Methods A total of 219 data sources …
health expenditures for 2021 and projections for 2045. Methods A total of 219 data sources …
Finer features for functional microdevices
S Kawata, HB Sun, T Tanaka, K Takada - Nature, 2001 - nature.com
… Hong-Bo Sun … Satoshi Kawata, Hong-Bo Sun, Tomokazu Tanaka & Kenji Takada …
Hong-Bo Sun …
Hong-Bo Sun …
Improved magnetic properties by treatment of iron-based rare earth intermetallic compounds in anmonia
JMD Coey, H Sun - Journal of Magnetism and magnetic materials, 1990 - Elsevier
The R 2 Fe 17 and R 2 Fe 17 C intermetallic compounds are found to absorb approximately
two atoms of nitrogen per formula unit on heating in ammonia or nitrogen. The interstitial …
two atoms of nitrogen per formula unit on heating in ammonia or nitrogen. The interstitial …
Generation of pathogenic TH17 cells in the absence of TGF-β signalling
…, JR Grainger, Q Chen, Y Kanno, WT Watford, HW Sun… - Nature, 2010 - nature.com
CD4 + T-helper cells that selectively produce interleukin (IL)-17 (T H 17), are critical for host
defence and autoimmunity 1 , 2 , 3 , 4 . Although crucial for T H 17 cells in vivo 5 , 6 , IL-23 …
defence and autoimmunity 1 , 2 , 3 , 4 . Although crucial for T H 17 cells in vivo 5 , 6 , IL-23 …
[HTML][HTML] Cross-reactive antibody responses to the 2009 pandemic H1N1 influenza virus
…, X Lu, W Zhong, EN Butler, H Sun… - New England journal …, 2009 - Mass Medical Soc
Background A new pandemic influenza A (H1N1) virus has emerged, causing illness globally,
primarily in younger age groups. To assess the level of preexisting immunity in humans …
primarily in younger age groups. To assess the level of preexisting immunity in humans …
[PDF][PDF] Global mapping of H3K4me3 and H3K27me3 reveals specificity and plasticity in lineage fate determination of differentiating CD4+ T cells
Multipotential naive CD4 + T cells differentiate into distinct lineages including T helper 1 (Th1),
Th2, Th17, and inducible T regulatory (iTreg) cells. The remarkable diversity of CD4 + T …
Th2, Th17, and inducible T regulatory (iTreg) cells. The remarkable diversity of CD4 + T …
TEP1, encoded by a candidate tumor suppressor locus, is a novel protein tyrosine phosphatase regulated by transforming growth factor β
DM Li, H Sun - Cancer research, 1997 - AACR
It has long been postulated that protein tyrosine phosphatases may act as tumor suppressors
because of their ability to counteract the oncogenic actions of protein tyrosine kinases. …
because of their ability to counteract the oncogenic actions of protein tyrosine kinases. …
PTEN modulates cell cycle progression and cell survival by regulating phosphatidylinositol 3, 4, 5,-trisphosphate and Akt/protein kinase B signaling pathway
H Sun, R Lesche, DM Li, J Liliental… - Proceedings of the …, 1999 - National Acad Sciences
To investigate the molecular basis of PTEN-mediated tumor suppression, we introduced a
null mutation into the mouse Pten gene by homologous recombination in embryonic stem (ES) …
null mutation into the mouse Pten gene by homologous recombination in embryonic stem (ES) …