Background—A reduction in compliance of the large-sized cardiothoracic (central) arteries
is an independent risk factor for the development of cardiovascular disease with advancing …

Background Arterial stiffness is an important risk factor for cardiovascular disease. Carotid-femoral
pulse wave velocity (cfPWV) is the most recognized and established index of arterial …

Older (‘Masters’) athletes strive to maintain or even improve upon the performance they
achieved at younger ages, but declines in athletic performance are inevitable with ageing. In this …

We determined the temporal effects of dietary sodium restriction on large elastic artery
compliance and systolic blood pressure (SBP) in 12 untreated, older (64±2 years) men and …

Background: Cross-sectional studies reported that chronic resistance training is associated
with arterial stiffening in men. These findings are in marked contrast to those found with …

OBJECTIVES We sought to determine a generalized equation for predicting maximal heart
rate (HR max ) in healthy adults. BACKGROUND The age-predicted HR max equation (ie, …

The tumor suppressor p53 is degraded by the ubiquitin-proteasome system. p53 was
polyubiquitinated in the presence of E1, UbcH5 as E2 and MDM2 oncoprotein. A ubiquitin …

We previously reported that osteoclast-like cells were formed in cocultures of a mouse
marrow-derived stromal cell line (ST2) with mouse spleen cells in the presence of 1 alpha, 25-…

Background—In sedentary humans endothelium-dependent vasodilation is impaired with
advancing age contributing to their increased cardiovascular risk, whereas endurance-trained …

Background— Reductions in the compliance of central arteries exert a number of adverse
effects on cardiovascular function and disease risk. Endurance training is efficacious in …