Improved silver staining of plant proteins, RNA and DNA in polyacrylamide gels

H Blum, H Beier, HJ Gross - Electrophoresis, 1987 - Wiley Online Library
A new modification of silver staining is presented which utilizes two chemical properties of
thiosulfate: image enhancement by pretreatment of fixed gels, and formation of soluble silver …

[HTML][HTML] Three exposures to the spike protein of SARS-CoV-2 by either infection or vaccination elicit superior neutralizing immunity to all variants of concern

…, S Krebs, V Fingerle, A Graf, P Steininger, H Blum… - Nature medicine, 2022 - nature.com
Infection-neutralizing antibody responses after severe acute respiratory syndrome coronavirus
2 (SARS-CoV-2) infection or coronavirus disease 2019 vaccination are an essential …

[HTML][HTML] LBR and lamin A/C sequentially tether peripheral heterochromatin and inversely regulate differentiation

…, D Devys, R Foisner, L Peichl, H Herrmann, H Blum… - Cell, 2013 - cell.com
Eukaryotic cells have a layer of heterochromatin at the nuclear periphery. To investigate
mechanisms regulating chromatin distribution, we analyzed heterochromatin organization in …

[PDF][PDF] Early IFN-α signatures and persistent dysfunction are distinguishing features of NK cells in severe COVID-19

…, B Kehr, A Keller, OT Keppler, S Kim-Hellmuth… - Immunity, 2021 - cell.com
Longitudinal analyses of the innate immune system, including the earliest time points, are
essential to understand the immunopathogenesis and clinical course of coronavirus disease (…

Trans-presentation of IL-6 by dendritic cells is required for the priming of pathogenic TH17 cells

…, HS Bartsch, K Sotlar, S Krebs, T Regen, H Blum… - Nature …, 2017 - nature.com
The cellular sources of interleukin 6 (IL-6) that are relevant for differentiation of the T H 17
subset of helper T cells remain unclear. Here we used a novel strategy for the conditional …

[HTML][HTML] Impaired detection of omicron by SARS-CoV-2 rapid antigen tests

…, M Muenchhoff, A Graf, S Krebs, H Blum… - Medical microbiology …, 2022 - Springer
Since autumn 2020, rapid antigen tests (RATs) have been implemented in several countries
as an important pillar of the national testing strategy to rapidly screen for infections on site …

Fine mapping of genome activation in bovine embryos by RNA sequencing

…, V Zakhartchenko, B Schwalb, H Blum… - Proceedings of the …, 2014 - National Acad Sciences
During maternal-to-embryonic transition control of embryonic development gradually switches
from maternal RNAs and proteins stored in the oocyte to gene products generated after …

Whole-exome sequencing in adult ETP-ALL reveals a high rate of DNMT3A mutations

…, S Vosberg, A Graf, S Krebs, H Blum… - Blood, The Journal …, 2013 - ashpublications.org
Early T-cell precursor (ETP) acute lymphoblastic leukemia (ALL) is a high-risk subgroup of T-lineage
ALL characterized by specific stem cell and myeloid features. In adult ETP-ALL, no …

[HTML][HTML] Comprehensive analysis of β-catenin target genes in colorectal carcinoma cell lines with deregulated Wnt/β-catenin signaling

A Herbst, V Jurinovic, S Krebs, SE Thieme, H Blum… - BMC genomics, 2014 - Springer
Background Deregulation of Wnt/β-catenin signaling is a hallmark of the majority of sporadic
forms of colorectal cancer and results in increased stability of the protein β-catenin. β-…

[HTML][HTML] Embryo-induced transcriptome changes in bovine endometrium reveal species-specific and common molecular markers of uterine receptivity

…, M Vermehren, F Sinowatz, H Blum… - …, 2006 - rep.bioscientifica.com
The endometrium plays a central role among the reproductive tissues in the context of early
embryo–maternal communication and pregnancy. This study investigated transcriptome …