Epithelial cell sheet formation is central to many aspects of vertebrate development and
function. For example, it is a major principle of differentiation in embryogenesis and regeneration…

Multiciliated cells (MCCs) promote fluid flow through coordinated ciliary beating, which requires
properly organized basal bodies (BBs). Airway MCCs have large numbers of BBs, which …

Apical constriction is critical for epithelial morphogenesis, including neural tube formation.
Vertebrate apical constriction is induced by di‐phosphorylated myosin light chain (ppMLC)‐…

The paracellular barrier function of tight junctions (TJs) in epithelial cell sheets is robustly
maintained against mechanical fluctuations, by molecular mechanisms that are poorly …

… My deep gratitude goes first to my laboratory colleagues Kanoh Hatsuho, Kazuhiro
Tateishi, and Yuki Ogura who shared the excitement of MTECs experiments. …

Recent developments in scanning electron microscopy (SEM) have resulted in a wealth of
new applications for cell and molecular biology, as well as related biological disciplines. It is …

Nuclear pore complexes (NPCs) are transport channels between the nucleus and the
cytoplasm. The NPCs are composed by around 30 different proteins, termed nucleoporins (Nups) …

Using MDCK cells that constitutively express a Förster resonance energy transfer biosensor,
we found that Rac1 activity is homogenous at the entire plasma membrane in early stages …

By analysing the cellular and subcellular events that occur in the centre of the developing
zebrafish neural rod, we have uncovered a novel mechanism of cell polarisation during lumen …

The conserved polarity complex, comprising the partitioning‐defective (Par) proteins Par3
and Par6, and the atypical protein kinase C, functions in various cell‐polarization events and …