Colitis caused by Clostridium difficile infection is a growing cause of human morbidity and
mortality, especially after antibiotic use in health care settings. The natural immunity of …

Prevention of multidrug-resistant (MDR) bacterial infections relies on accurate detection of
these organisms. We investigated shotgun metagenome sequencing for the detection of …

Clostridium difficile impairs Paneth cells, driving intestinal inflammation that exaggerates
colitis. Besides secreting bactericidal products to restrain C. difficile, Paneth cells act as …

Under conditions of altered microbial ecology, C. difficile incites epithelial injury and marked
intestinal inflammation, the primary determinant of disease outcome. Restoration of a …

Mechanisms underlying susceptibility to anthrax infection are unknown. Using a phylogenetically
diverse panel of inbred mice and spores of Bacillus anthracis Ames, we investigated …

Here, we constructed stable, chromosomal, constitutively expressed, green and red fluorescent
protein ( GFP and RFP ) as reporters in the select agents, Bacillus anthracis, Yersinia …

Here, we constructed stable, constitutively expressed, chromosomal green (GFP) and red
fluorescent (RFP) reporters in the genome of the surrogate strain, Francisella tularensis spp. …

The gastrointestinal (GI) environment is a complex ecosystem, where the host lives in complete
homeostasis with its microbiota, with the two generally maintaining a delicate balance (1, …

Presenting the latest molecular diagnostic techniques in one comprehensive volume The
molecular diagnostics landscape has changed dramatically since the last edition of Molecular …

Disclaimer: To the best of the publisher’s knowledge, this publication provides information
concerning the subject matter covered that is accurate as of the date of publication. The …