User profiles for Hans-Martin Jäck

Hans-Martin Jäck

Friedrich-Alexander University Erlangen-Nürnberg
Verified email at fau.de
Cited by 12191

[PDF][PDF] The Omicron variant is highly resistant against antibody-mediated neutralization: Implications for control of the COVID-19 pandemic

…, MS Winkler, M Lier, A Dopfer-Jablonka, HM Jäck… - Cell, 2022 - cell.com
The rapid spread of the SARS-CoV-2 Omicron variant suggests that the virus might become
globally dominant. Further, the high number of mutations in the viral spike protein raised …

Guidelines for the use of flow cytometry and cell sorting in immunological studies*

…, CA Hunter, A Iannone, HM Jäck… - European journal of …, 2017 - Wiley Online Library
From a technical point of view a flow cytometer is a light detection device capable of detecting
photons of different wavelengths over a high dynamic range. In order to achieve a high …

[PDF][PDF] SARS-CoV-2 variant B. 1.617 is resistant to bamlanivimab and evades antibodies induced by infection and vaccination

…, AS Moldenhauer, MS Winkler, S Schulz, HM Jäck… - Cell reports, 2021 - cell.com
The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants
threatens efforts to contain the coronavirus disease 2019 (COVID-19) pandemic. The …

Extensive immunoglobulin production sensitizes myeloma cells for proteasome inhibition

S Meister, U Schubert, K Neubert, K Herrmann… - Cancer research, 2007 - AACR
Multiple myeloma is an incurable plasma cell neoplasia characterized by the production of
large amounts of monoclonal immunoglobulins. The proteasome inhibitor bortezomib (PS-341…

[PDF][PDF] SARS-CoV-2 variants B. 1.351 and P. 1 escape from neutralizing antibodies

…, A Kempf, MS Winkler, S Schulz, HM Jäck… - Cell, 2021 - cell.com
The global spread of SARS-CoV-2/COVID-19 is devastating health systems and economies
worldwide. Recombinant or vaccine-induced neutralizing antibodies are used to combat the …

Serum microRNAs as powerful cancer biomarkers

J Wittmann, HM Jäck - Biochimica et Biophysica Acta (BBA)-Reviews on …, 2010 - Elsevier
MicroRNAs (miRNAs) are a class of small non-coding RNAs that regulate gene expression
at the posttranscriptional level by either degrading or blocking translation of messenger RNA …

hUPF2 silencing identifies physiologic substrates of mammalian nonsense-mediated mRNA decay

J Wittmann, EM Hol, HM Jäck - Molecular and cellular biology, 2006 - Taylor & Francis
Nonsense-mediated mRNA decay (NMD) is a conserved eukaryotic surveillance pathway
that selectively degrades aberrant mRNAs with premature termination codons (PTCs). …

Comparable neutralisation evasion of SARS-CoV-2 omicron subvariants BA. 1, BA. 2, and BA. 3

…, S Dickel, A Dopfer-Jablonka, HM Jäck… - The Lancet Infectious …, 2022 - thelancet.com
The SARS-CoV-2 omicron (B. 1.1. 529) variant has rapidly become globally dominant,
displacing the previously dominant delta (B1. 617.2) variant. The viral spike (S) protein is the key …

Augmented neutralisation resistance of emerging omicron subvariants BA. 2.12. 1, BA. 4, and BA. 5

…, A Cossmann, MV Stankov, HM Jäck… - The Lancet Infectious …, 2022 - thelancet.com
1 Arora P, Zhang L, Krüger N, et al. SARS-CoV-2 omicron sublineages show comparable
cell entry but differential neutralization by therapeutic antibodies. Cell Host Microbe 2022; …

[HTML][HTML] Omicron sublineage BQ. 1.1 resistance to monoclonal antibodies

…, A Kempf, I Nehlmeier, SR Schulz, HM Jäck… - The Lancet Infectious …, 2023 - thelancet.com
Vaccination represents the key strategy to control the COVID-19 pandemic through
induction of neutralising antibody responses and T cellassociated immunitythat substantially …