RNAi knock-down of the Litopenaeus vannamei Toll gene (LvToll) significantly increases mortality and reduces bacterial clearance after challenge with Vibrio harveyi

KCHC Wang, CW Tseng, HY Lin, IT Chen… - Developmental & …, 2010 - Elsevier
In this study, we used real-time PCR to simultaneously monitor the responses of 12 key genes
of the shrimp innate immune system in Litopenaeus vannamei after challenge with Vibrio …

The putative invertebrate adaptive immune protein Litopenaeus vannamei Dscam (LvDscam) is the first reported Dscam to lack a transmembrane domain and …

PH Chou, HS Chang, IT Chen, HY Lin, YM Chen… - Developmental & …, 2009 - Elsevier
It has recently been suggested that Dscam (Down syndrome cell adhesion molecule), a
member of the immunoglobulin superfamily (IgSF), plays an essential role in the alternative …

[HTML][HTML] Structural basis for calcium-stimulating pore formation of Vibrio α-hemolysin

…, YA Chen, H Chang, HY Lin, MC Ho, SM Lin - Nature …, 2023 - nature.com
Vibrio α-hemolysins (αHLs) are β-pore-forming toxins secreted by Vibrio pathogens, crucial
for the facilitation of bacterial infections through host cell lysis. These toxins are produced as …

[HTML][HTML] Betanodavirus induces phosphatidylserine exposure and loss of mitochondrial membrane potential in secondary necrotic cells, both of which are blocked by …

SP Chen, HL Yang, GM Her, HY Lin, MF Jeng, JL Wu… - Virology, 2006 - Elsevier
In this study, we show how the red spotted grouper nervous necrosis virus (RGNNV) causes
loss of mitochondrial membrane potential and promotes host secondary apoptotic necrosis. …

Picochlorum as an alternative to Nannochloropsis for grouper larval rearing

TY Chen, HY Lin, CC Lin, CK Lu, YM Chen - Aquaculture, 2012 - Elsevier
Nannochloropsis oculata is widely used in grouper larvae hatcheries for the production of
green water to stabilize water quality, provide shielding for light-sensitive fish larvae, and …

[HTML][HTML] Effects of Lactiplantibacillus plantarum PS128 on alleviating canine aggression and separation anxiety

YM Yeh, XY Lye, HY Lin, JY Wong, CC Wu… - Applied Animal …, 2022 - Elsevier
Certain strains of Lactiplantibacillus were found to have a positive impact on host neuromodulation
through the gut-brain axis and thus ameliorate emotional and behavioral problems. A …

[HTML][HTML] Multifunctional carbonized nanogels to treat lethal acute hepatopancreatic necrosis disease

…, HY Lin, LL Chen, CC Huang, HJ Lin - Journal of …, 2021 - Springer
Background Shrimp aquaculture has suffered huge economic losses over the past decade
due to the outbreak of acute hepatopancreatic necrosis disease (AHPND), which is mainly …

[HTML][HTML] Combination of multiplex reverse transcription recombinase polymerase amplification assay and capillary electrophoresis provides high sensitive and high …

SK Tsai, CC Chen, HJ Lin, HY Lin… - Journal of veterinary …, 2020 - ncbi.nlm.nih.gov
The pandemic of avian influenza viruses (AIVs) in Asia has caused enormous economic loss
in poultry industry and human health threat, especially clade 2.3. 4.4 H5 and H7 subtypes …

Crystal structures of dimeric and heptameric mtHsp60 reveal the mechanism of chaperonin inactivation

…, YA Chen, CH Yu, HY Lin, SM Lin - Life Science …, 2023 - life-science-alliance.org
Mitochondrial Hsp60 (mtHsp60) plays a crucial role in maintaining the proper folding of
proteins in the mitochondria. mtHsp60 self-assembles into a ring-shaped heptamer, which can …

Quantitative analysis of infectious precocity virus load and stunted growth syndrome via an immunohistochemical assay and reverse transcriptase quantitative real …

YR Chiang, YY Lu, HY Lin - Aquaculture, 2024 - Elsevier
The giant freshwater prawn Macrobrachium rosenbergii (M. rosenbergii) is susceptible to a
flavivirus known as the infectious precocity virus (IPV). The symptoms of infection, such as …