User profiles for Grace J Yuen
 | Grace J. YuenRagon Institute of MGH, MIT and Harvard Verified email at post.harvard.edu Cited by 1168 |
B lymphocytes and cancer: a love–hate relationship
B cells are abundant in many human tumors. In some tumors B cells may impede antitumor
immunity while in others they contribute to the immunological containment of cancer. The …
immunity while in others they contribute to the immunological containment of cancer. The …
[HTML][HTML] Identification of Pseudomonas aeruginosa Phenazines that Kill Caenorhabditis elegans
…, N Vinayavekhin, D Grenfell-Lee, GJ Yuen… - PLoS …, 2013 - journals.plos.org
Pathogenic microbes employ a variety of methods to overcome host defenses, including the
production and dispersal of molecules that are toxic to their hosts. Pseudomonas aeruginosa…
production and dispersal of molecules that are toxic to their hosts. Pseudomonas aeruginosa…
The expansion in lymphoid organs of IL-4+ BATF+ T follicular helper cells is linked to IgG4 class switching in vivo
…, VS Mahajan, SJH Murphy, GJ Yuen… - Life science …, 2018 - life-science-alliance.org
Distinct T follicular helper (T FH ) subsets that influence specific class-switching events are
assumed to exist, but the accumulation of isotype-specific T FH subsets in secondary …
assumed to exist, but the accumulation of isotype-specific T FH subsets in secondary …
Both live and dead Enterococci activate Caenorhabditis elegans host defense via immune and stress pathways
GJ Yuen, FM Ausubel - Virulence, 2018 - Taylor & Francis
The innate immune response of the nematode Caenorhabditis elegans has been extensively
studied and a variety of Toll-independent immune response pathways have been identified…
studied and a variety of Toll-independent immune response pathways have been identified…
Enterococcus infection biology: Lessons from invertebrate host models
GJ Yuen, FM Ausubel - Journal of microbiology, 2014 - Springer
The enterococci are commensals of the gastrointestinal tract of many metazoans, from insects
to humans. While they normally do not cause disease in the intestine, they can become …
to humans. While they normally do not cause disease in the intestine, they can become …
[HTML][HTML] The Role of Candida albicans SPT20 in Filamentation, Biofilm Formation and Pathogenesis
Candida albicans is a ubiquitous fungus, which can cause very serious and sometimes life-threatening
infections in susceptible patients. We used Caenorhabditis elegans as a model …
infections in susceptible patients. We used Caenorhabditis elegans as a model …
[HTML][HTML] B1a and B2 cells are characterized by distinct CpG modification states at DNMT3A-maintained enhancers
The B1 and B2 lineages of B cells contribute to protection from pathogens in distinct ways.
The role of the DNA CpG methylome in specifying these two B-cell fates is still unclear. Here …
The role of the DNA CpG methylome in specifying these two B-cell fates is still unclear. Here …
DOCK2 sets the threshold for entry into the virtual memory CD8+ T cell compartment by negatively regulating tonic TCR triggering
The control of cytoskeletal dynamics by dedicator of cytokinesis 2 (DOCK2), a hematopoietic
cell–specific actin effector protein, has been implicated in TCR signaling and T cell …
cell–specific actin effector protein, has been implicated in TCR signaling and T cell …
Autoimmunity in women: an eXamination of eXisting models
GJ Yuen - Clinical immunology, 2020 - Elsevier
Women comprise over 80% of the affected individuals for many autoimmune conditions.
Although sex-specific differences in sex hormones are thought to contribute to the female …
Although sex-specific differences in sex hormones are thought to contribute to the female …
DOCK2 sets the threshold for entry into the virtual memory CD8+ T cell compartment by negatively regulating tonic TCR triggering
The control of cytoskeletal dynamics by Dedicator of cytokinesis 2 (DOCK2), a hematopoietic
cell-specific actin effector protein, has been implicated in TCR signaling and T cell migration…
cell-specific actin effector protein, has been implicated in TCR signaling and T cell migration…