Sputum metalloproteinase-9/tissue inhibitor of metalloproteinase-1 ratio correlates with airflow obstruction in asthma and chronic bronchitis

…, M Profita, P Chanez, V Bellia, G Mautino… - American journal of …, 1998 - atsjournals.org
GISÈLE MAUTINOGISÈLE MAUTINOMautino G., Oliver N., Chanez P., Bousquet J.,
Capony F.Increased release of matrix metalloproteinase-9 in bronchoalveolar lavage fluid and by …

Transcriptional activation of apolipoprotein CIII expression by glucose may contribute to diabetic dyslipidemia

…, I Mertens, CH Samanez, G Mautino… - … , and vascular biology, 2011 - Am Heart Assoc
Objective— Hypertriglyceridemia and fatty liver are common in patients with type 2 diabetes,
but the factors connecting alterations in glucose metabolism with plasma and liver lipid …

Increased release of matrix metalloproteinase-9 in bronchoalveolar lavage fluid and by alveolar macrophages of asthmatics

G Mautino, N Oliver, P Chanez, J Bousquet… - American journal of …, 1997 - atsjournals.org
In order to determine whether matrix metalloproteinases (MMPs) contribute to inflammation
in asthma, we have examined the release of MMPs in bronchoalveolar lavage (BAL) fluids …

Glucose regulates the expression of the farnesoid X receptor in liver

D Duran-Sandoval, G Mautino, G Martin… - Diabetes, 2004 - Am Diabetes Assoc
An increased prevalence of hypertriglyceridemia and gallbladder disease occurs in patients
with diabetes or insulin resistance. Hypertriglyceridemia is positively associated to gall …

ATP-dependent mobilization of the glucocorticoid receptor during chromatin remodeling

TM Fletcher, N Xiao, G Mautino… - … and cellular biology, 2002 - Taylor & Francis
Chromatin remodeling by the glucocorticoid receptor (GR) is associated with activation of
transcription at the mouse mammary tumor virus (MMTV) promoter. We reconstituted this …

[HTML][HTML] Transcriptional regulation of human Rev-erbα gene expression by the orphan nuclear receptor retinoic acid-related orphan receptor α

E Raspe, G Mautino, C Duval, C Fontaine… - Journal of Biological …, 2002 - ASBMB
The Rev-erb and retinoic acid-related orphan receptors (ROR) are two related families of
orphan nuclear receptors that recognize similar response elements but have opposite effects …

Tissue inhibitor of metalloproteinase-1 levels in bronchoalveolar lavage fluid from asthmatic subjects

G Mautino, C Henriquet, D Jaffuel… - American journal of …, 1999 - atsjournals.org
Airway remodeling is a well-recognized feature in patients with chronic asthma. The accumulation
in the submucosa of fibrous proteins that are substrates of matrix metalloproteinases (…

Balance in asthma between matrix metalloproteinases and their inhibitors

G Mautino, F Capony, J Bousquet… - Journal of allergy and …, 1999 - jacionline.org
Mautino et al 531 smooth muscle, vascular remodeling, collagen deposition below the basement
membrane, and elastolysis. Is remodeling of the airways a proved clinical concept? 4 It …

Increased expression of tissue inhibitor of metalloproteinase-1 and loss of correlation with matrix metalloproteinase-9 by macrophages in asthma.

G Mautino, C Henriquet, C Gougat… - … ; a journal of technical …, 1999 - europepmc.org
Alveolar macrophages (AMs) can mediate tissue destruction and repair by synthesizing matrix
metalloproteinases (MMPs) and their inhibitors (TIMPs) as well as inflammatory cytokines, …

Transcriptional potencies of inhaled glucocorticoids

…, C Gougat, P Balaguer, G Mautino… - American journal of …, 2000 - atsjournals.org
Glucocorticoids (GC) are the most effective anti-inflammatory drugs used in asthma. By a
process called trans-activation, they increase the transcription of genes involved in either …