User profiles for Giorgio Oliviero

Giorgio Oliviero

Waters Corporation
Verified email at waters.com
Cited by 615

[PDF][PDF] The H3K36me2 methyltransferase Nsd1 demarcates PRC2-mediated H3K27me2 and H3K27me3 domains in embryonic stem cells

…, SG Jammula, A Scelfo, DJ Fitzpatrick, G Oliviero… - Molecular cell, 2018 - cell.com
The Polycomb repressor complex 2 (PRC2) is composed of the core subunits Ezh1/2, Suz12,
and Eed, and it mediates all di- and tri-methylation of histone H3 at lysine 27 in higher …

[PDF][PDF] A family of vertebrate-specific polycombs encoded by the LCOR/LCORL genes balance PRC2 subtype activities

…, E Jerman, E Healy, S Ito, D Holoch, G Oliviero… - Molecular cell, 2018 - cell.com
The polycomb repressive complex 2 (PRC2) consists of core subunits SUZ12, EED, RBBP4/7,
and EZH1/2 and is responsible for mono-, di-, and tri-methylation of lysine 27 on histone …

Resveratrol inhibits Epstein Barr Virus lytic cycle in Burkitt's lymphoma cells by affecting multiple molecular targets

A De Leo, G Arena, E Lacanna, G Oliviero, F Colavita… - Antiviral research, 2012 - Elsevier
Resveratrol (RV), a polyphenolic natural product present in many plants and fruits, exhibits
anti-inflammatory, cardio-protective and anti-proliferative properties. Moreover, RV affects a …

[HTML][HTML] Dynamic protein interactions of the polycomb repressive complex 2 during differentiation of pluripotent cells

G Oliviero, GL Brien, A Waston, G Streubel… - Molecular & Cellular …, 2016 - ASBMB
Polycomb proteins assemble to form complexes with important roles in epigenetic regulation.
The Polycomb Repressive Complex 2 (PRC2) modulates the di- and tri-methylation of …

Fam60a defines a variant Sin3a‐Hdac complex in embryonic stem cells required for self‐renewal

G Streubel, DJ Fitzpatrick, G Oliviero, A Scelfo… - The EMBO …, 2017 - embopress.org
Sin3a is the central scaffold protein of the prototypical Hdac1/2 chromatin repressor complex,
crucially required during early embryonic development for the growth of pluripotent cells of …

[HTML][HTML] The variant Polycomb Repressor Complex 1 component PCGF1 interacts with a pluripotency sub-network that includes DPPA4, a regulator of embryogenesis

G Oliviero, N Munawar, A Watson, G Streubel… - Scientific reports, 2015 - nature.com
PCGF1 encodes one of six human Polycomb RING finger homologs that are linked to
transcriptional repression and developmental gene regulation. Individual PCGF proteins define …

[HTML][HTML] Reconstruction and analysis of a large-scale binary Ras-effector signaling network

…, C Ternet, A Gourrege, K Wynne, G Oliviero… - Cell Communication and …, 2022 - Springer
Background Ras is a key cellular signaling hub that controls numerous cell fates via multiple
downstream effector pathways. While pathways downstream of effectors such as Raf, PI3K …

[HTML][HTML] Detection and quantitation of host cell proteins in monoclonal antibody drug products using automated sample preparation and data-independent acquisition …

L Strasser, G Oliviero, C Jakes, I Zaborowska… - Journal of …, 2021 - Elsevier
Ensuring the removal of host cell proteins (HCPs) during downstream processing of recombinant
proteins such as monoclonal antibodies (mAbs) remains a challenge. Since residual …

Distinct and diverse chromatin proteomes of ageing mouse organs reveal protein signatures that correlate with physiological functions

G Oliviero, S Kovalchuk, A Rogowska-Wrzesinska… - Elife, 2022 - elifesciences.org
Temporal molecular changes in ageing mammalian organs are of relevance to disease
aetiology because many age-related diseases are linked to changes in the transcriptional and …

[HTML][HTML] SETD1A Methyltransferase Is Physically and Functionally Linked to the DNA Damage Repair Protein RAD18*[S]

M Alsulami, N Munawar, E Dillon, G Oliviero… - Molecular & Cellular …, 2019 - ASBMB
SETD1A is a SET domain-containing methyltransferase involved in epigenetic regulation of
transcription. It is the main catalytic component of a multiprotein complex that methylates …