Boosting heterologous protein production in transgenic dicotyledonous seeds using Phaseolus vulgaris regulatory sequences

GD Jaeger, S Scheffer, A Jacobs, M Zambre… - Nature …, 2002 - nature.com
Over the past decade, several high value proteins have been produced in different transgenic
plant tissues such as leaves, tubers, and seeds 1 , 2 . Despite recent advances, many …

[HTML][HTML] A tandem affinity purification-based technology platform to study the cell cycle interactome in Arabidopsis thaliana

…, D Inze, E Witters, G De Jaeger - Molecular & Cellular …, 2007 - ASBMB
Defining protein complexes is critical to virtually all aspects of cell biology because many
cellular processes are regulated by stable protein complexes, and their identification often …

NINJA connects the co-repressor TOPLESS to jasmonate signalling

…, E Witters, D Inzé, JA Long, G De Jaeger… - Nature, 2010 - nature.com
Jasmonoyl-isoleucine (JA-Ile) is a plant hormone that regulates a broad array of plant
defence and developmental processes 1 , 2 , 3 , 4 , 5 . JA-Ile-responsive gene expression is …

[HTML][HTML] The TPLATE adaptor complex drives clathrin-mediated endocytosis in plants

…, E Witters, E Russinova, S Persson, G De Jaeger… - Cell, 2014 - cell.com
Clathrin-mediated endocytosis is the major mechanism for eukaryotic plasma membrane-based
proteome turn-over. In plants, clathrin-mediated endocytosis is essential for physiology …

Targeted interactomics reveals a complex core cell cycle machinery in Arabidopsis thaliana

…, D Inzé, E Witters, G De Jaeger - Molecular systems …, 2010 - embopress.org
Cell proliferation is the main driving force for plant growth. Although genome sequence analysis
revealed a high number of cell cycle genes in plants, little is known about the molecular …

Aberrant localization and underglycosylation of highly accumulating single-chain Fv-Fc antibodies in transgenic Arabidopsis seeds

…, M Liang, A Depicker, GD Jaeger - Proceedings of the …, 2007 - National Acad Sciences
Production of high-value recombinant proteins in transgenic seeds is an attractive and
economically feasible alternative to conventional systems based on mammalian cells and bacteria…

Identification of factors required for m6A mRNA methylation in Arabidopsis reveals a role for the conserved E3 ubiquitin ligase HAKAI

…, S El‐Showk, H Li, S Zhong, G De Jaeger… - New …, 2017 - Wiley Online Library
N6‐adenosine methylation (m 6 A) of mRNA is an essential process in most eukaryotes, but
its role and the status of factors accompanying this modification are still poorly understood. …

The Arabidopsis bHLH Transcription Factors MYC3 and MYC4 Are Targets of JAZ Repressors and Act Additively with MYC2 in the Activation of Jasmonate …

…, A Goossens, P Reymond, G De Jaeger… - The Plant …, 2011 - academic.oup.com
Jasmonates (JAs) trigger an important transcriptional reprogramming of plant cells to
modulate both basal development and stress responses. In spite of the importance of …

[HTML][HTML] Type II metacaspases Atmc4 and Atmc9 of Arabidopsis thaliana cleave substrates after arginine and lysine

D Vercammen, B Van De Cotte, G De Jaeger… - Journal of Biological …, 2004 - ASBMB
Nine potential caspase counterparts, designated metacaspases, were identified in the
Arabidopsis thaliana genome. Sequence analysis revealed two types of metacaspases, one with (…

ERF115 controls root quiescent center cell division and stem cell replenishment

…, S Vanderauwera, K Vandepoele, G De Jaeger… - Science, 2013 - science.org
The quiescent center (QC) plays an essential role during root development by creating a
microenvironment that preserves the stem cell fate of its surrounding cells. Despite being …