Background Plasmodium falciparum exhibits high translational plasticity during its development
in RBCs, yet the regulation at the post-transcriptional level is not well understood. The N …

In eukaryotes, cytosine methylation regulates diverse biological processes such as gene
expression, development and maintenance of genomic integrity. However, cytosine methylation …

Protein arginine methyltransferase 3 (PRMT3) regulates protein functions by introducing
asymmetric dimethylation marks at the arginine residues in proteins. However, very little is …

Among the proteins predicted to be a part of the DExD box RNA helicase family, the functions
of DDX49 are unknown. Here, we characterize the enzymatic activities and functions of …

Methylation of proteins is emerging to be an important regulator of protein function. SET7/9,
a protein lysine methyltransferase, catalyses methylation of several proteins involved in …

Plasmodium falciparum expresses clonally variant proteins on the surface of infected erythrocytes
to evade the host immune system. The clonally variant multigene families include var, …

The antigenic variation is an essential mechanism employed by the malaria parasite to
establish a chronic infection in humans. Three major virulent proteins EMP1, RIFINs, and …

Epigenetic modifications have emerged as critical regulators of virulence genes and stage-specific
gene expression in Plasmodium falciparum. However, the specific roles of histone …

Epigenetic machinery has emerged as a central player in gene regulation and chromatin
organization in Plasmodium spp. Epigenetic modifications on histones and their role in …

The emergence of COVID-19, caused by SARS-CoV-2 poses a significant threat to humans
as it is highly contagious with increasing mortality. There exists a high degree of …