The Zyggregator method for predicting protein aggregation propensities
GG Tartaglia, M Vendruscolo - Chemical Society Reviews, 2008 - pubs.rsc.org
… Gian Gaetano Tartaglia Gian Gaetano Tartaglia studied theoretical physics in Rome. He
then received his PhD in biochemistry at the University of Zurich in 2004, and he is currently …
then received his PhD in biochemistry at the University of Zurich in 2004, and he is currently …
Life on the edge: a link between gene expression levels and aggregation rates of human proteins
GG Tartaglia, S Pechmann, CM Dobson… - Trends in biochemical …, 2007 - cell.com
We have found that expression levels of human genes in vivo are remarkably anti-correlated
with the aggregation rates of the corresponding proteins measured in vitro by experiment. …
with the aggregation rates of the corresponding proteins measured in vitro by experiment. …
[HTML][HTML] Direct 3D printing of clear orthodontic aligners: current state and future possibilities
The recent introduction of three-dimensional (3D) printing is revolutionizing dentistry and is
even being applied to orthodontic treatment of malocclusion. Clear, personalized, removable …
even being applied to orthodontic treatment of malocclusion. Clear, personalized, removable …
[PDF][PDF] ALS/FTD mutation-induced phase transition of FUS liquid droplets and reversible hydrogels into irreversible hydrogels impairs RNP granule function
…, RR Ferry, L Dong, GG Tartaglia, G Favrin… - Neuron, 2015 - cell.com
The mechanisms by which mutations in FUS and other RNA binding proteins cause ALS and
FTD remain controversial. We propose a model in which low-complexity (LC) domains of …
FTD remain controversial. We propose a model in which low-complexity (LC) domains of …
[PDF][PDF] FUS phase separation is modulated by a molecular chaperone and methylation of arginine cation-π interactions
…, W Meadows, R Ferry, VJ Dardov, GG Tartaglia… - Cell, 2018 - cell.com
Reversible phase separation underpins the role of FUS in ribonucleoprotein granules and
other membrane-free organelles and is, in part, driven by the intrinsically disordered low-…
other membrane-free organelles and is, in part, driven by the intrinsically disordered low-…
[HTML][HTML] Amyloid-like aggregates sequester numerous metastable proteins with essential cellular functions
…, AC Woerner, S Pinkert, MH Hecht, GG Tartaglia… - Cell, 2011 - cell.com
Protein aggregation is linked with neurodegeneration and numerous other diseases by
mechanisms that are not well understood. Here, we have analyzed the gain-of-function toxicity of …
mechanisms that are not well understood. Here, we have analyzed the gain-of-function toxicity of …
Review of hydrogen storage by adsorption in carbon nanotubes
FL Darkrim, P Malbrunot, GP Tartaglia - International Journal of Hydrogen …, 2002 - Elsevier
… BET surface of 285 m 2 g −1 , which they have themselves determined, taking as reference
the adsorption — not given — of Saran carbon having a BET surface of 1600 m 2 g −1 . In an …
the adsorption — not given — of Saran carbon having a BET surface of 1600 m 2 g −1 . In an …
Single tooth bite forces in healthy young adults
…, G Serrao, C Dellavia, GM Tartaglia - Journal of oral …, 2004 - Wiley Online Library
The assessment of bite forces on healthy single tooth appears essential for a correct
quantification of the actual impact of single implant oral rehabilitations. In the present study, a new …
quantification of the actual impact of single implant oral rehabilitations. In the present study, a new …
Metastability of native proteins and the phenomenon of amyloid formation
An experimental determination of the thermodynamic stabilities of a series of amyloid fibrils
reveals that this structural form is likely to be the most stable one that protein molecules can …
reveals that this structural form is likely to be the most stable one that protein molecules can …
Prediction of aggregation-prone regions in structured proteins
GG Tartaglia, AP Pawar, S Campioni… - Journal of molecular …, 2008 - Elsevier
We present a method for predicting the regions of the sequences of peptides and proteins
that are most important in promoting their aggregation and amyloid formation. The method …
that are most important in promoting their aggregation and amyloid formation. The method …