User profiles for Franziska Völlmy
 | Franziska VollmyUtrecht University Verified email at uu.nl Cited by 167 |
A serum proteome signature to predict mortality in severe COVID-19 patients
Here, we recorded serum proteome profiles of 33 severe COVID-19 patients admitted to
respiratory and intensive care units because of respiratory failure. We received, for most patients…
respiratory and intensive care units because of respiratory failure. We received, for most patients…
Systemic LRG1 expression in melanoma is associated with disease progression and recurrence
EP Hoefsmit, F Völlmy, EA Rozeman, ILM Reijers… - Cancer research …, 2023 - AACR
The response rates upon neoadjuvant immune checkpoint blockade (ICB) in stage III melanoma
are higher as compared with stage IV disease. Given that successful ICB depends on …
are higher as compared with stage IV disease. Given that successful ICB depends on …
[HTML][HTML] Farnesylated heat shock protein 40 is a component of membrane-bound RISC in Arabidopsis
L Sjögren, M Floris, A Barghetti, F Völlmy… - Journal of Biological …, 2018 - ASBMB
ARGONAUTE1 (AGO1) binds directly to small regulatory RNA and is a key effector protein
of post-transcriptional gene silencing mediated by microRNA (miRNA) and small interfering …
of post-transcriptional gene silencing mediated by microRNA (miRNA) and small interfering …
[HTML][HTML] Into the Dark Serum Proteome: Personalized Features of IgG1 and IgA1 Repertoires in Severe COVID-19 Patients
Serum proteomics has matured and is now able to monitor hundreds of proteins quantitatively
in large cohorts of patients. However, the fine characteristics of some of the most dominant …
in large cohorts of patients. However, the fine characteristics of some of the most dominant …
[HTML][HTML] The Q-junction and the inflammatory response are critical pathological and therapeutic factors in CoQ deficiency
Defects in Coenzyme Q (CoQ) metabolism have been associated with primary mitochondrial
disorders, neurodegenerative diseases and metabolic conditions. The consequences of …
disorders, neurodegenerative diseases and metabolic conditions. The consequences of …
No patient is the same; lessons learned from antibody repertoire profiling in hospitalized severe COVID-19 patients
Here, by using mass spectrometry-based methods IgG1 and IgA1 clonal repertoires were
monitored quantitatively and longitudinally in more than 50 individual serum samples obtained …
monitored quantitatively and longitudinally in more than 50 individual serum samples obtained …
NODAL/TGFβ signalling mediates the self-sustained stemness induced by PIK3CAH1047R homozygosity in pluripotent stem cells
Activating PIK3CA mutations are known ‘drivers’ of human cancer and developmental
overgrowth syndromes. We recently demonstrated that the ‘hotspot’ PIK3CA H1047R variant …
overgrowth syndromes. We recently demonstrated that the ‘hotspot’ PIK3CA H1047R variant …
[HTML][HTML] The role of Pseudo-Orthocaspase (SyOC) of Synechocystis sp. PCC 6803 in attenuating the effect of oxidative stress
Caspases are proteases, best known for their involvement in the execution of apoptosis—a
subtype of programmed cell death, which occurs only in animals. These proteases are …
subtype of programmed cell death, which occurs only in animals. These proteases are …
High-dose oncogenic PIK3CA drives constitutive cellular stemness through self-sustained TGFβ pathway activation
Oncogenic PIK3CA mutations activate phosphoinositide 3-kinase-alpha (PI3Kα) and are
among the commonest somatic mutations in cancer. We recently demonstrated that the “hotspot…
among the commonest somatic mutations in cancer. We recently demonstrated that the “hotspot…
Is there a serum proteome signature to predict mortality in severe COVID-19 patients?(preprint)
Here we recorded serum proteome profiles of 33 COVID-19 patients admitted to respiratory
and intensive care units because of respiratory failure. We received, for most patients, blood …
and intensive care units because of respiratory failure. We received, for most patients, blood …