User profiles for Fok-Moon Lum
Fok Moon LumInvestigator Verified email at idlabs.a-star.edu.sg Cited by 2758 |
[HTML][HTML] Monkeypox: disease epidemiology, host immunity and clinical interventions
Monkeypox virus (MPXV), which causes disease in humans, has for many years been restricted
to the African continent, with only a handful of sporadic cases in other parts of the world. …
to the African continent, with only a handful of sporadic cases in other parts of the world. …
Reduced development of COVID-19 in children reveals molecular checkpoints gating pathogenesis illuminating potential therapeutics
JB Steinman, FM Lum, PPK Ho… - Proceedings of the …, 2020 - National Acad Sciences
The reduced development of COVID-19 for children compared to adults provides some
tantalizing clues on the pathogenesis and transmissibility of this pandemic virus. First, ACE2, the …
tantalizing clues on the pathogenesis and transmissibility of this pandemic virus. First, ACE2, the …
Cellular and molecular mechanisms of chikungunya pathogenesis
FM Lum, LFP Ng - Antiviral research, 2015 - Elsevier
Chikungunya virus (CHIKV) is an arthropod-borne virus that causes chikungunya fever, a
disease characterized by the onset of fever and rashes, with arthralgia as its hallmark symptom…
disease characterized by the onset of fever and rashes, with arthralgia as its hallmark symptom…
A pathogenic role for CD4+ T cells during Chikungunya virus infection in mice
Chikungunya virus (CHIKV) is an alphavirus that causes chronic and incapacitating
arthralgia in humans. Injury to the joint is believed to occur because of viral and host immune-…
arthralgia in humans. Injury to the joint is believed to occur because of viral and host immune-…
Early neutralizing IgG response to Chikungunya virus in infected patients targets a dominant linear epitope on the E2 glycoprotein
Chikungunya virus (CHIKV) and related arboviruses have been responsible for large epidemic
outbreaks with serious economic and social impact. The immune mechanisms, which …
outbreaks with serious economic and social impact. The immune mechanisms, which …
[HTML][HTML] Viperin restricts chikungunya virus replication and pathology
…, SS Foo, D Simamarta, FM Lum… - The Journal of …, 2012 - Am Soc Clin Investig
Chikungunya virus (CHIKV) is a mosquito-borne arthralgia arbovirus that is reemergent in
sub-Saharan Africa and Southeast Asia. CHIKV infection has been shown to be self-limiting, …
sub-Saharan Africa and Southeast Asia. CHIKV infection has been shown to be self-limiting, …
[HTML][HTML] An essential role of antibodies in the control of Chikungunya virus infection
In recent years, Chikungunya virus (CHIKV) was responsible for epidemic outbreaks in
intertropical regions. Although acquired immunity has been shown to be crucial during CHIKV …
intertropical regions. Although acquired immunity has been shown to be crucial during CHIKV …
Zika virus infects human fetal brain microglia and induces inflammation
Background. The unprecedented reemergence of Zika virus (ZIKV) has startled the world with
reports of increased microcephaly in Brazil. ZIKV can infect human neural progenitors and …
reports of increased microcephaly in Brazil. ZIKV can infect human neural progenitors and …
[HTML][HTML] Paradoxical effect of chloroquine treatment in enhancing chikungunya virus infection
…, SD Thiberville, L Dupuis-Maguiraga, FM Lum… - Viruses, 2018 - mdpi.com
Since 2005, Chikungunya virus (CHIKV) re-emerged and caused numerous outbreaks in
the world, and finally, was introduced into the Americas in 2013. The lack of CHIKV-specific …
the world, and finally, was introduced into the Americas in 2013. The lack of CHIKV-specific …
Caribbean and La Reunion chikungunya virus isolates differ in their capacity to induce proinflammatory Th1 and NK cell responses and acute joint pathology
Chikungunya virus (CHIKV) is a mosquito-borne arthralgic alphavirus that has garnered
international attention as an important emerging pathogen since 2005. More recently, it invaded …
international attention as an important emerging pathogen since 2005. More recently, it invaded …