User profiles for Fabio Ticconi
Fabio TicconiUniklinik RWTH Aachen Verified email at rwth-aachen.de Cited by 168 |
Cyclin E1 and cyclin-dependent kinase 2 are critical for initiation, but not for progression of hepatocellular carcinoma
…, R Weiskirchen, F Ticconi… - Proceedings of the …, 2018 - National Acad Sciences
E-type cyclins E1 (CcnE1) and E2 (CcnE2) are regulatory subunits of cyclin-dependent kinase
2 (Cdk2) and thought to control the transition of quiescent cells into the cell cycle. Initial …
2 (Cdk2) and thought to control the transition of quiescent cells into the cell cycle. Initial …
Resident regulatory T cells reflect the immune history of individual lymph nodes
Regulatory T cells (T regs ) are present in lymphoid and nonlymphoid tissues where they
restrict immune activation, prevent autoimmunity, and regulate inflammation. T regs in …
restrict immune activation, prevent autoimmunity, and regulate inflammation. T regs in …
[HTML][HTML] LINC00152 Drives a Competing Endogenous RNA Network in Human Hepatocellular Carcinoma
Genomic and epigenomic studies revealed dysregulation of long non-coding RNAs in many
cancer entities, including liver cancer. We identified an epigenetic mechanism leading to …
cancer entities, including liver cancer. We identified an epigenetic mechanism leading to …
[PDF][PDF] Cognate recognition of microbial antigens defines constricted CD4+ T cell receptor repertoires in the inflamed colon
M Muschaweck, L Kopplin, F Ticconi, A Schippers… - Immunity, 2021 - cell.com
Key aspects of intestinal T cells, including their antigen specificity and their selection by the
microbiota and other intestinal antigens, as well as the contribution of individual T cell clones …
microbiota and other intestinal antigens, as well as the contribution of individual T cell clones …
Variants of DNMT3A cause transcript-specific DNA methylation patterns and affect hematopoiesis
T Božić, J Frobel, A Raic, F Ticconi… - Life science …, 2018 - life-science-alliance.org
De novo DNA methyltransferase 3A (DNMT3A) plays pivotal roles in hematopoietic
differentiation. In this study, we followed the hypothesis that alternative splicing of DNMT3A has …
differentiation. In this study, we followed the hypothesis that alternative splicing of DNMT3A has …
Genetic barcoding systematically compares genes in del(5q) MDS and reveals a central role for CSNK1A1 in clonal expansion
USA Stalmann, F Ticconi, IAM Snoeren, R Li… - Blood …, 2022 - ashpublications.org
How genetic haploinsufficiency contributes to the clonal dominance of hematopoietic stem
cells (HSCs) in del(5q) myelodysplastic syndrome (MDS) remains unresolved. Using a …
cells (HSCs) in del(5q) myelodysplastic syndrome (MDS) remains unresolved. Using a …
Dissecting CD8+ T cell pathology of severe SARS-CoV-2 infection by single-cell epitope mapping
F Schreibing, M Hannani, F Ticconi, E Fewings… - BioRxiv, 2021 - biorxiv.org
The current COVID-19 pandemic represents a global challenge. A better understanding of the
immune response against SARS-CoV-2 is key to unveil the differences in disease severity …
immune response against SARS-CoV-2 is key to unveil the differences in disease severity …
[HTML][HTML] Cyclin E1 in murine and human liver cancer: a promising target for therapeutic intervention during tumour progression
Simple Summary The cell cycle regulator Cyclin E1 is a key mediator and biomarker of liver
cancer progression in mice and man independent of its canonical interacting partner Cyclin-…
cancer progression in mice and man independent of its canonical interacting partner Cyclin-…
Device monitoring of heart failure in cardiac resynchronization therapy device recipients: a single-center experience with a novel multivector impedance monitoring …
…, DG Della Rocca, A Politano, F Ticconi… - Journal of …, 2013 - journals.lww.com
Objectives We investigated the performance of a new intrathoracic multivector impedance
monitoring system for the prediction of heart failure events in consecutive device-implanted …
monitoring system for the prediction of heart failure events in consecutive device-implanted …
[HTML][HTML] Transcription factor motif enrichment in whole transcriptome analysis identifies STAT4 and BCL6 as the most prominent binding motif in systemic juvenile …
…, N Fischer, K Ohl, B Denecke, F Ticconi… - Arthritis Research & …, 2018 - Springer
Background The term systemic juvenile idiopathic arthritis (sJIA) describes an autoinflammatory
condition characterized by arthritis and severe systemic inflammation, which in later …
condition characterized by arthritis and severe systemic inflammation, which in later …