A follow-up on quantitative and qualitative olfactory dysfunction and other symptoms in patients recovering from COVID-19 smell loss

…, J de Groot, S Boesveldt, S Bhutani, EM Weir… - Rhinology, 2022 - shs.hal.science
Background: Sudden smell loss is a specific early symptom of COVID-19, which, prior to the
emergence of Omicron, had estimated prevalence of ~40% to 75%. Chemosensory …

[PDF][PDF] The AAA ATPase MDN1 acts as a SUMO-targeted regulator in mammalian pre-ribosome remodeling

N Raman, E Weir, S Müller - Molecular cell, 2016 - cell.com
Biogenesis of translation-competent 80S ribosomes is a multi-step process requiring the
sequential action of non-ribosomal trans-acting factors. We previously identified the human …

Increasing incidence of parosmia and phantosmia in patients recovering from COVID-19 smell loss

…, J de Groot, S Boesveldt, S Bhutani, EM Weir… - MedRxiv, 2021 - medrxiv.org
Importance Sudden smell loss is a specific early symptom of COVID-19, with an estimated
prevalence of ∼40% to 75%. Smell impairment affects physical and mental health, and …

Massively collaborative crowdsourced research on COVID19 and the chemical senses: Insights and outcomes

EM Weir, DR Reed, MY Pepino, MG Veldhuizen… - Food quality and …, 2022 - Elsevier
In March 2020, the Global Consortium of Chemosensory Research (GCCR) was founded by
chemosensory researchers to address emerging reports of unusual smell and taste …

Transient loss and recovery of oral chemesthesis, taste and smell with COVID-19: A small case-control series

EM Weir, C Exten, RC Gerkin, SD Munger… - Physiology & …, 2023 - Elsevier
Transient loss of smell is a common symptom of influenza and other upper respiratory infections.
Loss of taste is possible but rare with these illnesses, and patient reports of ‘taste loss’ …

The Adaptive Olfactory Measure of Threshold (ArOMa-T): A rapid test of olfactory function

EM Weir, ME Hannum, DR Reed, PV Joseph… - Chemical …, 2022 - academic.oup.com
Many widely used psychophysical olfactory tests have limitations that can create barriers to
adoption. For example, tests that measure the ability to identify odors may confound sensory …

Biochemical and functional characterization of a meiosis-specific Pch2/ORC AAA+ assembly

…, RC da Silva, M Firlej, D Pan, E Weir… - Life science …, 2020 - life-science-alliance.org
Pch2 is a meiosis-specific AAA+ protein that controls several important chromosomal processes.
We previously demonstrated that Orc1, a subunit of the ORC, functionally interacts with …

Measuring Olfactory And Chemosensory Function In Healthy Controls And COVID-19 Positive Individuals

E Weir - 2022 - etda.libraries.psu.edu
Olfactory function has historically been neglected despite its importance to overall health
and wellbeing. Our sense of smell serves many functions, both physiological and emotional. …

A meiosis-specific AAA+ assembly reveals repurposing of ORC during budding yeast gametogenesis

…, D Pan, E Weir, A Sarembe, VB Raina, JR Weir… - BioRxiv, 2019 - biorxiv.org
ORC (Orc1-6) is an AAA+ complex that loads the AAA+ MCM helicase to replication origins.
Orc1, a subunit of ORC, functionally interacts with budding yeast Pch2, a meiosis-specific …

[HTML][HTML] Massively collaborative crowdsourced research on COVID19 and the chemical senses

E Weir, D Reed, MY Pepino, M Veldhuizen, J Hayes - 2021 - europepmc.org
In March 2020, the Global Consortium of Chemosensory Research (GCCR) was founded by
chemosensory researchers to address then emerging reports of unusual smell and taste …